IPCS INCHEM Home
1,3-BUTADIENE
ICSC: 0017
Peer-Review Status: 04.12.2000 Validated
Divinyl
Vinylethylene 
CAS #: 106-99-0 RTECS #: EI9275000
UN #: 1010 (stabilized)
EC #: 601-013-00-X
EINECS #: 203-450-8
    Formula: C4H6 / CH2=(CH)2=CH2
Molecular mass: 54.1

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Extremely flammable.  NO open flames, NO sparks and NO smoking.  Shut off supply; if not possible and no risk to surroundings, let the fire burn itself out. In other cases extinguish with water spray, powder, carbon dioxide. 
EXPLOSION Gas/air mixtures are explosive.  Closed system, ventilation, explosion-proof electrical equipment and lighting. Prevent build-up of electrostatic charges (e.g., by grounding) if in liquid state.  In case of fire: keep cylinder cool by spraying with water. 
 
EXPOSURE   AVOID ALL CONTACT! AVOID EXPOSURE OF (PREGNANT) WOMEN!   
Inhalation Cough. Sore throat. Dizziness. Headache. Drowsiness. Blurred vision. Nausea. Unconciousness.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin ON CONTACT WITH LIQUID: FROSTBITE.  Cold-insulating gloves.  ON FROSTBITE: rinse with plenty of water, do NOT remove clothes. Refer for medical attention . 
Eyes Redness. Pain. Blurred vision. See Skin.  Wear safety goggles.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion   Do not eat, drink, or smoke during work.   

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Remove all ignition sources. Evacuate danger area! Consult an expert! Personal protection: chemical protection suit including self-contained breathing apparatus. Ventilation. NEVER direct water jet on liquid.  Do not transport with food and feedstuffs. 
EC Classification
Symbol: F+, T; R: 45-46-12; S: 53-45; Note: D 
UN Classification
UN Hazard Class: 2.1 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-20S1010.
NFPA Code: H2; F4; R2. 
Fireproof. Cool. Separated from food and feedstuffs. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS COMPRESSED LIQUEFIED GAS WITH CHARACTERISTIC ODOUR. 

Physical dangers
The gas is heavier than air and may travel along the ground; distant ignition possible. As a result of flow, agitation, etc., electrostatic charges can be generated. Vapours are uninhibited and may polymerize, causing blockage of vents. 

Chemical dangers
The substance can form peroxides on exposure to air, initiating explosive polymerization. The substance may polymerize due to warming. This generates fire or explosion hazard. Mixtures with copper and its alloys are shock-sensitive. See Notes. Decomposes explosively on rapid heating under pressure. Reacts vigorously with oxidants and many other substances. This generates fire and explosion hazard. 

Occupational exposure limits
TLV: 2ppm as TWA; A2 (suspected human carcinogen); (ACGIH 2004).
MAK: Carcinogen category: 1; Germ cell mutagen group: 2; (DFG 2004). 

Routes of exposure
The substance can be absorbed into the body by inhalation. 

Inhalation risk
A harmful concentration of this gas in the air will be reached very quickly on loss of containment. 

Effects of short-term exposure
The substance is irritating to the eyes and respiratory tract. Rapid evaporation of the liquid may cause frostbite. The substance may cause effects on the central nervous system. This may result in lowering of consciousness. 

Effects of long-term or repeated exposure
The substance may have effects on the bone marrow. This may result in leukemia. This substance is probably carcinogenic to humans. May cause heritable genetic damage to human germ cells. Animal tests show that this substance possibly causes toxic effects upon human reproduction. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: -4°C
Melting point: -109°C
Relative density (water = 1): 0.6
Solubility in water, g/100ml: 0.1 (none)
Vapour pressure, kPa at 20°C: 245
Relative vapour density (air = 1): 1.9
Flash point: -76°C
Auto-ignition temperature: 414°C
Explosive limits, vol% in air: 1.1-16.3
Octanol/water partition coefficient as log Pow: 1.99  
 

NOTES
Piping material for this gas must not contain over 63% of copper.
Use of alcoholic beverages enhances the harmful effect.
The odour warning when the exposure limit value is exceeded is insufficient.
Card has been partly updated in October 2004 and April 2005.
See sections Occupational Exposure Limits, EU classification, Emergency Response. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations