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BENZYL CHLORIDE
ICSC: 0016
Peer-Review Status: 18.10.2001 Validated
alpha-Chlorotoluene
(Chloromethyl)benzene
Tolyl chloride 
CAS #: 100-44-7 RTECS #: XS8925000
UN #: 1738
EC #: 602-037-00-3
EINECS #: 202-853-6
    Formula: C7H7Cl / C6H5CH2Cl
Molecular mass: 126.6

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames.  Use powder, AFFF, foam, carbon dioxide. 
EXPLOSION Above 67°C explosive vapour/air mixtures may be formed.  Above 67°C use a closed system and ventilation.  In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE   AVOID ALL CONTACT! AVOID EXPOSURE OF (PREGNANT) WOMEN!   
Inhalation Burning sensation. Cough. Nausea. Headache. Shortness of breath. Dizziness.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Half-upright position. Refer for medical attention. 
Skin MAY BE ABSORBED! Redness. Pain.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention . 
Eyes Watering of the eyes. Redness. Pain. Blurred vision. Severe deep burns.  Wear safety goggles or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal pain. Diarrhoea. Vomiting. Burning sensation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in covered non-metallic containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.  Do not transport with food and feedstuffs. 
EC Classification
Symbol: T; R: 45-22-23-37/38-41-48/22; S: 53-45; Note: E 
UN Classification
UN Hazard Class: 6.1; UN Subsidiary Risks: 8; UN Pack Group: II 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61S1738.
NFPA Code: H2; F2; R1. 
Separated from food and feedstuffs and incompatible materials. See Chemical Dangers. Dry. Ventilation along the floor. Store only if stabilized. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS LIQUID WITH PUNGENT ODOUR. 

Physical dangers
 

Chemical dangers
The substance polymerizes under the influence of all common metals except nickel and lead. This produces corrosive fumes (hydrogen chloride - see ICSC 0163). This generates fire or explosion hazard. On combustion, forms toxic and corrosive fumes of hydrogen chloride. Reacts vigorously with strong oxidants. Attacks many metals in the presence of water. 

Occupational exposure limits
TLV: 1ppm as TWA; A3 (confirmed animal carcinogen with unknown relevance to humans); (ACGIH 2001).
MAK: Carcinogen category: 2; Skin absorption (H); (DFG 2004). 

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion. 

Inhalation risk
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C ; on spraying much faster. 

Effects of short-term exposure
The substance is corrosive to the eyes. The vapour is irritating to the eyes, skin and respiratory tract. Inhalation of of the vapour or aerosol may cause lung oedema. See Notes. The substance may cause effects on the central nervous system. This may result in unconsciousness. 

Effects of long-term or repeated exposure
The substance may have effects on the liver and kidneys. This may result in tissue lesions. This substance is possibly carcinogenic to humans. Animal tests show that this substance possibly causes toxicity to human reproduction or development. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 179°C
Melting point: ~-43°C
Relative density (water = 1): 1.1
Solubility in water, g/100ml: <0.1 (none)
Vapour pressure, Pa at 20°C: 120
Relative vapour density (air = 1): 4.4
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00
Flash point: 67°C c.c.
Auto-ignition temperature: 585°C
Explosive limits, vol% in air: 1.1-14.0
Octanol/water partition coefficient as log Pow: 2.3  
The substance is toxic to aquatic organisms. 

NOTES
Depending on the degree of exposure, periodic medical examination is suggested.
The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort.
Rest and medical observation are therefore essential.
Immediate administration of an appropriate inhalation therapy by a doctor or a person authorized by him/her, should be considered.
An added stabilizer or inhibitor can influence the toxicological properties of this substance, consult an expert.
Card has been partly updated in April 2005.
See section Occupational Exposure Limits. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.
    See Also:
       Toxicological Abbreviations
       Benzyl chloride (SIDS)
       Benzyl Chloride (IARC Summary & Evaluation, Volume 11, 1976)
       Benzyl Chloride (IARC Summary & Evaluation, Volume 29, 1982)