IPCS INCHEM Home
ANILINEICSC: 0011
April 2014
CAS #: 62-53-3Benzeneamine
Aminobenzene
Phenylamine
UN #: 1547
EINECS #: 200-539-3

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Combustible. Gives off irritating or toxic fumes (or gases) in a fire.  Above 76°C explosive vapour/air mixtures may be formed.  NO open flames. NO contact with oxidizing agents.  Above 76°C use a closed system and ventilation.  Use water spray, powder, foam, carbon dioxide.  In case of fire: keep drums, etc., cool by spraying with water. 

 PREVENT GENERATION OF MISTS! STRICT HYGIENE! See Notes.  
  SYMPTOMS ACUTE HAZARDS FIRST AID
Inhalation Blue lips, fingernails and skin. Headache. Dizziness. Nausea. Vomiting. Weakness. Laboured breathing. Convulsions.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Administration of oxygen may be needed. Refer immediately for medical attention. See Notes. 
Skin EASILY ABSORBED! Redness. Further see Inhalation.  Protective gloves. Protective clothing.  Administration of oxygen may be needed. Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer immediately for medical attention. See Notes. 
Eyes Redness. Pain. Corneal damage.  Wear face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion See Inhalation.  Do not eat, drink, or smoke during work.  Administration of oxygen may be needed. Rinse mouth. Do NOT induce vomiting. Rest. Refer immediately for medical attention. See Notes. 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Evacuate danger area! Consult an expert! Personal protection: chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. 

According to UN GHS Criteria

skull;toxiccancer;health hazenviro;aqua
DANGER
Toxic if swallowed, in contact with skin or if inhaled
Causes damage to red blood cells
Causes damage to the blood through prolonged or repeated exposure
Causes serious eye irritation
May cause an allergic skin reaction
Very toxic to aquatic life 

Transportation
UN Classification
UN Hazard Class: 6.1; UN Pack Group: II 

STORAGE
Separated from strong oxidants, strong acids and food and feedstuffs. Well closed. Provision to contain effluent from fire extinguishing. Store in an area without drain or sewer access. 
PACKAGING
Do not transport with food and feedstuffs. 
ANILINE ICSC: 0011
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS OILY LIQUID WITH CHARACTERISTIC ODOUR. TURNS BROWN ON EXPOSURE TO AIR OR LIGHT. 

Physical dangers
 

Chemical dangers
Decomposes above 190°C . This produces toxic and corrosive fumes of nitrogen oxides and ammonia and flammable vapours. Reacts with strong acids and strong oxidants. This generates fire and explosion hazard. Attacks copper and its alloys. 

Formula: C6H7N / C6H5NH2
Molecular mass: 93.1
Boiling point: 184°C
Melting point: -6°C
Relative density (water = 1): 1.02
Solubility in water, g/100ml at 20°C: 3.4
Vapour pressure, Pa at 20°C: 40
Relative vapour density (air = 1): 3.2
Flash point: 76°C c.c.
Auto-ignition temperature: 630°C
Explosive limits, vol% in air: 1.2-11.0
Octanol/water partition coefficient as log Pow: 0.94  


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin also as a vapour and by ingestion. 

Effects of short-term exposure
The substance is severely irritating to the eyes. The substance may cause effects on the blood. This may result in the formation of methaemoglobin. See Notes. Exposure could cause haemolysis. This may result in haemolytic anaemia. The effects may be delayed. Medical observation is indicated. 

Inhalation risk
A harmful contamination of the air will be reached on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster. 

Effects of long-term or repeated exposure
Repeated or prolonged contact may cause skin sensitization. The substance may have effects on the blood. This may result in haemolytic anaemia. 


Occupational exposure limits
TLV: 2 ppm as TWA; (skin); A3 (confirmed animal carcinogen with unknown relevance to humans); BEI issued.
MAK: 7.7 mg/m3, 2 ppm; peak limitation category: II(2); skin absorption (H); sensitization of skin (SH); carcinogen category: 4; pregnancy risk group: C 

ENVIRONMENT
The substance is very toxic to aquatic organisms. It is strongly advised not to let the chemical enter into the environment. 

NOTES
In case of blue lips, fingernails or skin treatment with 100% oxygen may be needed; the appropriate means with instructions must be available.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
Specific treatment with antidotes like methylene blue can not be used for pregnant women and persons with a G6PD enzyme deficiency. These people should avoid all contact.
The odour warning when the exposure limit value is exceeded is insufficient. 

ADDITIONAL INFORMATION
  EC Classification
Symbol: T, N; R: 23/24/25-40-41-43-48/23/24/25-68-50; S: (1/2)-26-27-36/37/39-45-46-63-61 

All rights reserved. The published material is being distributed without warranty of any kind, either expressed or implied. Neither ILO nor WHO nor the European Commission shall be responsible for the interpretation and use of the information contained in this material.
    See Also:
       Toxicological Abbreviations
       Aniline  (IARC Summary & Evaluation, Supplement7, 1987)
       Aniline (IARC Summary & Evaluation, Volume 4, 1974)