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0 ANILINE
ICSC: 0011
Peer-Review Status: 15.03.2001 Validated
Benzeneamine
Aminobenzene
Phenylamine 
CAS #: 62-53-3 RTECS #: BW6650000
UN #: 1547
EC #: 612-008-00-7
EINECS #: 200-539-3
    Formula: C6H7N / C6H5NH2
Molecular mass: 93.1

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames. NO contact with oxidizing agents.  Use water spray, powder, foam, carbon dioxide. 
EXPLOSION Above 70°C explosive vapour/air mixtures may be formed.  Above 70°C use a closed system and ventilation.  In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE   AVOID ALL CONTACT!   
Inhalation Blue lips, fingernails and skin. Headache. Dizziness. Laboured breathing. Convulsions. Increased heart rate. Vomiting. Weakness. Unconciousness. Symptoms may be delayed. See Notes.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin MAY BE ABSORBED! Redness. Further see Inhalation.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes Redness. Pain.  Wear face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Further see Inhalation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention . See Notes. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.  Do not transport with food and feedstuffs. 
EC Classification
Symbol: T, N; R: 23/24/25-40-41-43-48/23/24/25-68-50; S: (1/2)-26-27-36/37/39-45-46-63-61 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: II 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61S1547.
NFPA Code: H3; F2; R0. 
Separated from strong oxidants, strong acids and food and feedstuffs. Well closed. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS OILY LIQUID WITH CHARACTERISTIC ODOUR. TURNS BROWN ON EXPOSURE TO AIR OR LIGHT. 

Physical dangers
 

Chemical dangers
Decomposes above 190°C . This produces toxic and corrosive fumes of nitrogen oxides and ammonia and flammable vapours. The substance is a weak base. Reacts with strong oxidants. This generates fire and explosion hazard. Reacts with strong acids. Attacks copper and its alloys. 

Occupational exposure limits
TLV: 2ppm as TWA; (skin); A3 (confirmed animal carcinogen with unknown relevance to humans); BEI issued; (ACGIH 2004).
MAK: 2 ppm, 7.7 mg/m³; Carcinogen category: 3B; Peak limitation category: II(2); Pregnancy risk group: C; Germ cell mutagen group: 4; Skin absorption (H); Sensitization of skin (SH); (DFG 2006). 

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion. 

Inhalation risk
A harmful contamination of the air will be reached on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster. 

Effects of short-term exposure
The substance is irritating to the eyes and skin. The substance may cause effects on the blood. This may result in formation of methaemoglobin. Exposure at high levels could cause death. Medical observation is indicated. The effects may be delayed. See Notes. 

Effects of long-term or repeated exposure
Repeated or prolonged contact may cause skin sensitization. The substance may have effects on the blood. This may result in formation of methaemoglobin. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 184°C
Melting point: -6°C
Relative density (water = 1): 1.02
Solubility in water, g/100ml at 20°C: 3.4
Vapour pressure, Pa at 20°C: 40
Relative vapour density (air = 1): 3.2
Flash point: 70°C c.c.
Auto-ignition temperature: 615°C
Explosive limits, vol% in air: 1.2-11
Octanol/water partition coefficient as log Pow: 0.94  
The substance is very toxic to aquatic organisms. 

NOTES
Use of alcoholic beverages enhances the harmful effect.
Depending on the degree of exposure, periodic medical examination is indicated.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
The odour warning when the exposure limit value is exceeded is insufficient.
Card has been partly updated in October 2004.
See sections Occupational Exposure Limits, EU classification, Emergency Response. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.
    See Also:
       Toxicological Abbreviations
       Aniline  (IARC Summary & Evaluation, Supplement7, 1987)
       Aniline (IARC Summary & Evaluation, Volume 4, 1974)