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PARATHIONICSC: 0006
April 2004
CAS #: 56-38-2O,O-Diethyl-O-(4-nitrophenyl)phosphorothioate
Phosphorothioic acid O,O-diethyl O-(4-nitrophenyl) ester
Ethyl parathion
UN #: 3018
EINECS #: 200-271-7

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Combustible. Gives off irritating or toxic fumes (or gases) in a fire. Liquid formulations containing organic solvents may be flammable.    NO open flames.    Use water spray, dry powder, carbon dioxide.  In case of fire: keep drums, etc., cool by spraying with water. 

 PREVENT GENERATION OF MISTS! STRICT HYGIENE! AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN! IN ALL CASES CONSULT A DOCTOR! 
  SYMPTOMS ACUTE HAZARDS FIRST AID
Inhalation Pupillary constriction, muscle cramp, excessive salivation. Sweating. Nausea. Vomiting. Dizziness. Headache. Convulsions. Diarrhoea. Weakness. Laboured breathing. Wheezing. Unconsciousness.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Artificial respiration may be needed. Refer for medical attention. 
Skin MAY BE ABSORBED! Further see Inhalation.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes MAY BE ABSORBED! Redness. Pain. Blurred vision.  Wear face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal cramps. Diarrhoea. Vomiting. Further see Inhalation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Give a slurry of activated charcoal in water to drink. Refer for medical attention . See Notes. 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Evacuate danger area! Consult an expert! Personal protection: chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking liquid in sealable containers. Treat remaining liquid with an alkaline substance. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. 

According to UN GHS Criteria

 

Transportation
UN Classification
UN Hazard Class: 6.1; UN Pack Group: I 

STORAGE
Provision to contain effluent from fire extinguishing. Separated from strong oxidants and food and feedstuffs. Well closed. Keep in a well-ventilated room. 
PACKAGING
Do not transport with food and feedstuffs.
Severe marine pollutant. 
PARATHION ICSC: 0006
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
PALE YELLOW-TO-BROWN (TECHNICAL-GRADE PRODUCT) LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
No data. 

Chemical dangers
Decomposes above 200°C . This produces toxic gases including carbon monoxide, nitrogen oxides, phosphorous oxides and sulfur oxides. Reacts with strong oxidants. Attacks some forms of plastic, rubber and coatings. 

Formula: (C2H5O)2PSOC6H4NO2
Molecular mass: 291.3
Boiling point: 375°C
Melting point: 6°C
Relative density (water = 1): 1.26
Solubility in water, g/100ml at 25°C: 0.002
Flash point: 120°C
Octanol/water partition coefficient as log Pow: 3.8  


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol, through the skin, by ingestion and through the eyes. 

Effects of short-term exposure
The substance may cause effects on the nervous system. This may result in convulsions, respiratory failure and muscle weakness. Cholinesterase inhibition. Exposure could cause death. The effects may be delayed. Medical observation is indicated. 

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying. 

Effects of long-term or repeated exposure
Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms. 


Occupational exposure limits
TLV: 0.05 mg/m3, ppm, as TWA; (skin); A4 (not classifiable as a human carcinogen); BEI issued.
MAK: (inhalable fraction): 0.1 mg/m3; peak limitation category: II(8); skin absorption (H); pregnancy risk group: D 

ENVIRONMENT
The substance is very toxic to aquatic organisms. This substance may be hazardous to the environment. Special attention should be given to birds. The substance may cause long-term effects in the aquatic environment. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal. 

NOTES
Depending on the degree of exposure, periodic medical examination is suggested.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
If the substance is formulated with solvents also consult the ICSCs of these materials.
Carrier solvents used in commercial formulations may change physical and toxicological properties.
The odour warning when the exposure limit value is exceeded is insufficient.
Do NOT take working clothes home. 

ADDITIONAL INFORMATION
  EC Classification
Symbol: T+, N; R: 24-26/28-48/25-50/53; S: (1/2)-28-36/37-45-60-61 

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    See Also:
       Toxicological Abbreviations
       Parathion (HSG 74, 1992)
       Parathion (FAO Meeting Report PL/1965/10/1)
       Parathion (FAO/PL:1967/M/11/1)
       Parathion (FAO/PL:1969/M/17/1)
       Parathion (AGP:1970/M/12/1)
       Parathion (Pesticide residues in food: 1984 evaluations)
       Parathion (Pesticide residues in food: 1995 evaluations Part II Toxicological & Environmental)
       Parathion (IARC Summary & Evaluation, Volume 30, 1983)