IPCS INCHEM Home

International Agency for Research on Cancer (IARC) - Summaries & Evaluations

BENZO[ghi]FLUORANTHENE

VOL.: 32 (1983) (p. 171)

CAS No.: 203-12-3
Chem. Abstr. Name: Benzo(ghi)fluoranthene

5. Summary of Data Reported and Evaluation

5.1 Experimental data

Benzo[ghi]fluoranthene was tested for carcinogenicity in one study in female mice by skin painting; no skin tumour was observed.

No data on the teratogenicity of this compound were available.

In the one available study, benzo[ghi]fluoranthene was mutagenic to Salmonella typhimurium in the presence of an exogenous metabolic system.

There is inadequate evidence that benzo[ghi]fluoranthene is active in short-term tests.

5.2 Human data

Benzo[ghi]fluoranthene is present as a component of the total content of polynuclear aromatic compounds in the environment. Human exposure to benzo[ghi]fluoranthene occurs primarily through the smoking of tobacco, inhalation of polluted air and by ingestion of food and water contaminated by combustion effluents.

5.3 Evaluation

The available data are inadequate to permit an evaluation of the carcinogenicity of benzo[ghi]fluoranthene to experimental animals.

For definition of the italicized terms, see Preamble Evaluation.

Subsequent evaluation: Suppl. 7 (1987) (p. 58: Group 3)

Synonyms


Last updated: 17 April 1998






















    See Also:
       Toxicological Abbreviations