VOL.: 20 (1979) (p. 155)
Hexachlorobenzene is foetotoxic and produces some teratogenic effects. It was not mutagenic in yeast and did not induce dominant lethal effects in male rats.
The production and use of hexachlorobenzene as a fungicide over the past several decades and its occurrence as a byproduct in the manufacture of other chemicals indicate that widespread human exposure occurs in both the general and working environments. This is confirmed by many reports of its occurrence in the general environment and in human body fluids.
A group of people who were accidentally exposed over a period of time is known to exist; many of these showed toxic manifestations, some lasting for as long as 20 years. No data on carcinogenic effects have been reported.
For definition of the italicized terms, see Preamble Evaluation.
Subsequent evaluations: Suppl. 7 (1987); Vol. 79 (2001)
See Also: Toxicological Abbreviations Hexachlorobenzene (EHC 195, 1997) Hexachlorobenzene (HSG 107, 1998) Hexachlorobenzene (ICSC) Hexachlorobenzene (PIM 256) Hexachlorobenzene (FAO/PL:1969/M/17/1) Hexachlorobenzene (WHO Pesticide Residues Series 4) Hexachlorobenzene (IARC Summary & Evaluation, Volume 79, 2001)