International Agency for Research on Cancer (IARC) - Summaries & Evaluations


VOL.: 16 (1978) (p. 145)

CAS No.: 494-38-2
Chem. Abstr. Name: N,N,N',N'-Tetramethyl-3,6-acridinediamine

5. Summary of Data Reported and Evaluation

5.1 Animal data

Acridine orange has been tested in mice by skin application, in mice and rats by repeated subcutaneous injection and in mice by single intraperitoneal injection followed by skin application of croton oil. The available data are insufficient for an evaluation of the carcinogenicity of this compound to be made.

5.2 Human data

No case reports or epidemiological studies were available to the Working Group.

Subsequent evaluation: Suppl. 7 (1987) (p. 56: Group 3)

For definition of Groups, see Preamble Evaluation.


Last updated: 26 March 1998

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