VOL.: 13 (1977) (p. 101)
Chem. Abstr. Name: 8-Quinolinol
Positive results were obtained in bladder implantation experiments when 8-hydroxyquinoline was incorporated in cholesterol pellets but were negative when paraffin wax pellets were employed (see also introduction, in this volume). Its application intravaginally in different vehicles to mice and rats did not significantly increase the incidence of tumours when compared with that in appropriate controls.
No evaluation of the carcinogenicity of 8-hydroxyquinoline can be made on the basis of the available data (however, see also the results obtained in mutagenicity studies).
N.B. - Data on the copper chelate of 8-hydroxyquinoline were discussed, but because its chemical properties and uses are different from those of 8-hydroxyquinoline it will be considered by a further Working Group.
Subsequent evaluation: Suppl. 7 (1987) (p. 64: Group 3)
For definition of Groups, see Preamble Evaluation.
See Also: Toxicological Abbreviations