JECFA Evaluations-CYPERMETHRIN-

Summary of Evaluations Performed by the
Joint FAO/WHO Expert Committee on Food Additives

CYPERMETHRIN
Chemical names:	(RS)-alpha-CYANO-3-PHENOXYBENZYL-(1RS,3RS,1RS,3RS)-3-(2,2-DICHLOROVINYL)-2,2-DIMETHYLCYCLOPROPANE CARBOXYLATE (IUPAC); (RS)-CYANO(3-PHENOXYPHENYL)METHYL(1RS)-cis-trans-3-(2,2-DICHLOROETHENYL)-2,2-DIMETHYLCYCLOPROPANE CARBOXYLATE (CAS)
Functional class:	VETERINARY DRUG (INSECTICIDE)
Latest evaluation:	2004
ADI:	0-0.02 mg/kg
Comments:	Group ADI for cypermethrin and alpha-cypermethrin
Comments/MRLs:	MRLs (total of cypermethrin residues resulting from the use of cypermethrin or alpha-cypermethrin as veterinary drugs): Muscle, liver, and kidney (cattle and sheep): 0.05 mg/kg; fat (cattle and sheep): 1 mg/kg; milk (cattle and sheep): 0.1 mg/kg
Report:	TRS 925-JECFA 62/12
Specifications:	FNP 41/16-JECFA 62/11
Tox monograph:	FAS 53-JECFA 62/91
Previous status:	2002, TRS 911-JECFA 58/37, FAS 38-JECFA 47/133 (1996), FNP 41/14-JECFA 58/15. 0-0.05 mg/kg bw (1996). MRLS, AS CYPERMETHRIN: MUSCLE, LIVER AND KIDNEY (SHEEP): 0.02 mg/kg; FAT (SHEEP): 0.2 mg/kg. FU. MRL 2000, TRS 900-JECFA 54/41, FNP 41/13-JECFA 54/19, FAS 38-JECFA 47/133 (1996). 0-0.05 mg/kg bw (1996). THE TEMPORARY MRLs RECOMMENDED AT THE FORTY-SEVENTH MEETING (1996) WERE NOT EXTENDED AS THE INFORMATION REQUIRED BY THE FIFTH-FOURTH MEETING (2000) WAS NOT PROVIDED AND THERE WAS NO INDICATION THAT IT WOULD BE PROVIDED IN THE FUTURE. FU. NOT EXTENDED 1996, TRS 876-JECFA 47/44, FNP 41/9-JECFA 47/4, FAS 38-JECFA 47/133. 0-0.05. MRLS (TEMPORARY; EXPRESSED AS PARENT DRUG): MUSCLE, LIVER AND KIDNEY (CATTLE, SHEEP AND CHICKENS): 0.2 mg/kg; FAT (CATTLE, SHEEP AND CHICKENS): 1 mg/kg; EGGS (CHICKENS): 0.1 mg/kg; MILK (CATTLE): 0.05 mg/l. FU. TMRL

28 Jan 06