ICSC 1556 - TRIMETHYL PHOSPHITE

TRIMETHYL PHOSPHITE	ICSC: 1556 (October 2004)
Phophorous acid, trimethyl ester Trimethoxy phosphine Methyl phosphite

CAS #: 121-45-9

UN #: 2329

EC Number: 204-471-5

	ACUTE HAZARDS	PREVENTION	FIRE FIGHTING
FIRE & EXPLOSION	Flammable. Gives off irritating or toxic fumes (or gases) in a fire. Above 23°C explosive vapour/air mixtures may be formed.	NO open flames, NO sparks and NO smoking. Above 23°C use a closed system, ventilation and explosion-proof electrical equipment.	Use foam, carbon dioxide, powder. In case of fire: keep drums, etc., cool by spraying with water. NO direct contact with water.

AVOID EXPOSURE OF (PREGNANT) WOMEN!
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	Cough. Sore throat.	Use ventilation, local exhaust or breathing protection.	Fresh air, rest.
Skin	Redness. Pain.	Protective gloves.	Rinse and then wash skin with water and soap.
Eyes	Redness. Pain.	Wear safety spectacles.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion		Do not eat, drink, or smoke during work.	Rinse mouth.

SPILLAGE DISPOSAL	CLASSIFICATION & LABELLING
Personal protection: self-contained breathing apparatus. Collect leaking and spilled liquid in sealable containers as far as possible.	According to UN GHS Criteria Transportation UN Classification UN Hazard Class: 3; UN Pack Group: III
STORAGE
Fireproof. Separated from oxidants and strong bases.
PACKAGING

TRIMETHYL PHOSPHITE

ICSC: 1556

PHYSICAL & CHEMICAL INFORMATION
Physical State; Appearance COLOURLESS LIQUID WITH PUNGENT ODOUR. Physical dangers Chemical dangers On combustion, forms toxic fumes including phosphine and phosphorus oxides. Reacts with water. This produces methanol and dimethyl phosphite. Reacts with oxidants and strong bases. Reacts with magnesium perchlorate. This generates explosion hazard.	Formula: C₃H₉O₃P / (CH₃O)₃P Molecular mass: 124.1 Boiling point: 111.5°C Melting point: -78°C Relative density (water = 1): 1.1 Solubility in water: reaction Vapour pressure, kPa at 25°C: 3.2 Relative vapour density (air = 1): 4.3 Flash point: 23°C c.c. Auto-ignition temperature: 250°C

PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS LIQUID WITH PUNGENT ODOUR.

Physical dangers

Chemical dangers
On combustion, forms toxic fumes including phosphine and phosphorus oxides. Reacts with water. This produces methanol and dimethyl phosphite. Reacts with oxidants and strong bases. Reacts with magnesium perchlorate. This generates explosion hazard.

Formula: C₃H₉O₃P / (CH₃O)₃P
Molecular mass: 124.1
Boiling point: 111.5°C
Melting point: -78°C
Relative density (water = 1): 1.1
Solubility in water: reaction
Vapour pressure, kPa at 25°C: 3.2
Relative vapour density (air = 1): 4.3
Flash point: 23°C c.c.
Auto-ignition temperature: 250°C

EXPOSURE & HEALTH EFFECTS
Routes of exposure The substance can be absorbed into the body through the skin and by ingestion. Effects of short-term exposure The substance is severely irritating to the eyes and skin.	Inhalation risk A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C. Effects of long-term or repeated exposure Animal tests show that this substance possibly causes toxicity to human reproduction or development.

EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body through the skin and by ingestion.

Effects of short-term exposure
The substance is severely irritating to the eyes and skin.

Inhalation risk
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C.

Effects of long-term or repeated exposure
Animal tests show that this substance possibly causes toxicity to human reproduction or development.

OCCUPATIONAL EXPOSURE LIMITS
TLV: 2 ppm as TWA. MAK skin absorption (H)

ENVIRONMENT
Environmental effects from the substance have not been investigated adequately.

NOTES

ADDITIONAL INFORMATION

EC Classification

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    See Also:
       Toxicological Abbreviations