ICSC 0941 - PROPYLAMINE

PROPYLAMINE	ICSC: 0941 (November 2009)
n-Propylamine 1-Aminopropane Propanamine

CAS #: 107-10-8

UN #: 1277

EC Number: 203-462-3

	ACUTE HAZARDS	PREVENTION	FIRE FIGHTING
FIRE & EXPLOSION	Highly flammable. Gives off irritating or toxic fumes (or gases) in a fire. Vapour/air mixtures are explosive.	NO open flames, NO sparks and NO smoking. Closed system, ventilation, explosion-proof electrical equipment and lighting. Do NOT use compressed air for filling, discharging, or handling.	Use powder, alcohol-resistant foam, water in large amounts, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water.

STRICT HYGIENE! IN ALL CASES CONSULT A DOCTOR!
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	Cough. Sore throat. Laboured breathing. Shortness of breath. Symptoms may be delayed. See Notes.	Use ventilation, local exhaust or breathing protection.	Fresh air, rest. Half-upright position. Refer immediately for medical attention.
Skin	Redness. Pain. Serious skin burns.	Protective gloves. Protective clothing.	First rinse with plenty of water for at least 15 minutes, then remove contaminated clothes and rinse again. Refer immediately for medical attention.
Eyes	Watering of the eyes. Redness. Pain. Blurred vision. Severe burns. Loss of vision.	Wear face shield or eye protection in combination with breathing protection.	Rinse with plenty of water (remove contact lenses if easily possible). Refer immediately for medical attention.
Ingestion	Burns in mouth and throat. Burning sensation in the throat and chest. Abdominal pain. Vomiting. Diarrhoea. Shock or collapse.	Do not eat, drink, or smoke during work.	Rinse mouth. Do NOT induce vomiting. Refer immediately for medical attention.

SPILLAGE DISPOSAL	CLASSIFICATION & LABELLING
Remove all ignition sources. Evacuate danger area! Consult an expert! Personal protection: gas-tight chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.	According to UN GHS Criteria DANGER Highly flammable liquid and vapour Toxic in contact with skin or if inhaled Harmful if swallowed Causes severe skin burns and eye damage May cause respiratory irritation Harmful to aquatic life Transportation UN Classification UN Hazard Class: 3; UN Subsidiary Risks: 8; UN Pack Group: II
STORAGE
Provision to contain effluent from fire extinguishing. Fireproof. Separated from strong oxidants, strong acids and food and feedstuffs. Dry. Well closed. Store in an area without drain or sewer access.
PACKAGING
Unbreakable packaging. Put breakable packaging into closed unbreakable container. Do not transport with food and feedstuffs.

PROPYLAMINE

ICSC: 0941

PHYSICAL & CHEMICAL INFORMATION
Physical State; Appearance COLOURLESS HYGROSCOPIC LIQUID WITH CHARACTERISTIC ODOUR. Physical dangers The vapour is heavier than air and may travel along the ground; distant ignition possible. Chemical dangers Decomposes on burning. This produces toxic fumes including nitrogen oxides. The solution in water is a medium strong base. Reacts violently with strong acids, many compounds such as halogenated hydrocarbons, alcohols and nitroparaffins. Reacts violently with oxidants and mercury. This generates fire and explosion hazard. Attacks metals such as aluminium, copper, tin and zinc.	Formula: C₃H₉N / CH₃(CH₂)₂NH₂ Molecular mass: 59.1 Boiling point: 48°C Melting point: -83°C Relative density (water = 1): 0.7. Solubility in water: miscible Vapour pressure, kPa at 20°C: 33.9 Relative vapour density (air = 1): 2.0 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.3 Flash point: <-37°C Auto-ignition temperature: 320°C Explosive limits, vol% in air: 2.0-10.4 Octanol/water partition coefficient as log Pow: 0.15

PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS HYGROSCOPIC LIQUID WITH CHARACTERISTIC ODOUR.

Physical dangers
The vapour is heavier than air and may travel along the ground; distant ignition possible.

Chemical dangers
Decomposes on burning. This produces toxic fumes including nitrogen oxides. The solution in water is a medium strong base. Reacts violently with strong acids, many compounds such as halogenated hydrocarbons, alcohols and nitroparaffins. Reacts violently with oxidants and mercury. This generates fire and explosion hazard. Attacks metals such as aluminium, copper, tin and zinc.

Formula: C₃H₉N / CH₃(CH₂)₂NH₂
Molecular mass: 59.1
Boiling point: 48°C
Melting point: -83°C
Relative density (water = 1): 0.7.
Solubility in water: miscible
Vapour pressure, kPa at 20°C: 33.9
Relative vapour density (air = 1): 2.0
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.3
Flash point: <-37°C
Auto-ignition temperature: 320°C
Explosive limits, vol% in air: 2.0-10.4
Octanol/water partition coefficient as log Pow: 0.15

EXPOSURE & HEALTH EFFECTS
Routes of exposure The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion. Serious local effects by all routes of exposure. Effects of short-term exposure The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. Inhalation may cause lung oedema, but only after initial corrosive effects on eyes and/or airways have become manifest. Exposure could cause severe swelling of the throat.	Inhalation risk A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C. Effects of long-term or repeated exposure Repeated or prolonged contact with skin may cause dermatitis. The substance may have effects on the respiratory tract and lungs. This may result in chronic inflammation and impaired functions.

EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion. Serious local effects by all routes of exposure.

Effects of short-term exposure
The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. Inhalation may cause lung oedema, but only after initial corrosive effects on eyes and/or airways have become manifest. Exposure could cause severe swelling of the throat.

Inhalation risk
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C.

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. The substance may have effects on the respiratory tract and lungs. This may result in chronic inflammation and impaired functions.

OCCUPATIONAL EXPOSURE LIMITS

ENVIRONMENT
The substance is harmful to aquatic organisms.

NOTES
Do NOT take working clothes home. The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential.

ADDITIONAL INFORMATION

EC Classification

All rights reserved. The published material is being distributed without warranty of any kind, either expressed or implied. Neither ILO nor WHO nor the European Commission shall be responsible for the interpretation and use of the information contained in this material.

    See Also:
       Toxicological Abbreviations
       PROPYLAMINE (JECFA Evaluation)