ICSC 0449 - DIISOPROPYLAMINE

DIISOPROPYLAMINE	ICSC: 0449 (November 2019)
DIPA N-(1-Methylethyl)-2-propanamine

CAS #: 108-18-9

UN #: 1158

EC Number: 203-558-5

	ACUTE HAZARDS	PREVENTION	FIRE FIGHTING
FIRE & EXPLOSION	Highly flammable. Gives off irritating or toxic fumes (or gases) in a fire. Vapour/air mixtures are explosive. Risk of fire and explosion on contact with strong oxidizing agents.	NO open flames, NO sparks and NO smoking. NO contact with strong oxidizing agents. Closed system, ventilation, explosion-proof electrical equipment and lighting. Prevent build-up of electrostatic charges (e.g., by grounding).	Use alcohol-resistant foam, water, powder, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water.

PREVENT GENERATION OF MISTS! AVOID ALL CONTACT! IN ALL CASES CONSULT A DOCTOR!
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	Cough. Sore throat. Burning sensation. Shortness of breath. Laboured breathing.	Use ventilation, local exhaust or breathing protection.	Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer immediately for medical attention.
Skin	Redness. Pain. Serious skin burns.	Protective gloves. Protective clothing.	Wear protective gloves when administering first aid. Remove contaminated clothes. See Notes. Rinse skin with plenty of water or shower for at least 15 minutes. Refer immediately for medical attention.
Eyes	Redness. Pain. Blurred vision. Severe burns.	Wear face shield or eye protection in combination with breathing protection.	Rinse with plenty of water for several minutes (remove contact lenses if easily possible). Refer immediately for medical attention.
Ingestion	Burns in mouth and throat. Burning sensation behind the breastbone. Abdominal pain. Vomiting. Shock or collapse.	Do not eat, drink, or smoke during work.	Rinse mouth. Give nothing to drink. Do NOT induce vomiting. Refer immediately for medical attention.

SPILLAGE DISPOSAL	CLASSIFICATION & LABELLING
Remove all ignition sources. Evacuate danger area! Consult an expert! Personal protection: chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Cover the spilled material with inert absorbent or sand. Then store and dispose of according to local regulations. Do NOT wash away into sewer.	According to UN GHS Criteria DANGER Highly flammable liquid and vapour Harmful if swallowed Causes severe skin burns and eye damage May cause respiratory irritation Harmful to aquatic life Transportation UN Classification UN Hazard Class: 3; UN Subsidiary Risks: 8; UN Pack Group: II
STORAGE
Fireproof. Separated from strong oxidants, strong acids and food and feedstuffs. Store only in original container. Store in an area without drain or sewer access.
PACKAGING
Do not transport with food and feedstuffs.

DIISOPROPYLAMINE

ICSC: 0449

PHYSICAL & CHEMICAL INFORMATION
Physical State; Appearance COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. Physical dangers The vapour is heavier than air and may travel along the ground; distant ignition possible. Chemical dangers Decomposes on burning. This produces toxic fumes including nitrogen oxides. The substance is a strong base. Reacts violently with strong oxidants. This generates fire and explosion hazard. Attacks metals and many plastics. Solutions in water slowly etch glass.	Formula: C₆H₁₅N / CH₃CH(CH₃)NHCH(CH₃)CH₃ Molecular mass: 101.2 Boiling point: 84°C Melting point: -61°C Relative density (water = 1): 0.72 Solubility in water, g/l: 10 (slightly soluble) Explosive limits, vol% in air: 0.8-7.1 Vapour pressure, kPa at 20°C: 9.3 Relative vapour density (air = 1): 3.5 Flash point: -6°C o.c. Octanol/water partition coefficient as log Pow: 1.64 Auto-ignition temperature: 316°C

PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR.

Physical dangers
The vapour is heavier than air and may travel along the ground; distant ignition possible.

Chemical dangers
Decomposes on burning. This produces toxic fumes including nitrogen oxides. The substance is a strong base. Reacts violently with strong oxidants. This generates fire and explosion hazard. Attacks metals and many plastics. Solutions in water slowly etch glass.

Formula: C₆H₁₅N / CH₃CH(CH₃)NHCH(CH₃)CH₃
Molecular mass: 101.2
Boiling point: 84°C
Melting point: -61°C
Relative density (water = 1): 0.72
Solubility in water, g/l: 10 (slightly soluble)
Explosive limits, vol% in air: 0.8-7.1
Vapour pressure, kPa at 20°C: 9.3
Relative vapour density (air = 1): 3.5
Flash point: -6°C o.c.
Octanol/water partition coefficient as log Pow: 1.64
Auto-ignition temperature: 316°C

EXPOSURE & HEALTH EFFECTS
Routes of exposure Serious local effects by all routes of exposure. Effects of short-term exposure The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. Contact of the vapour with the eyes may cause visual disturbances. Exposure could cause asphyxiation due to swelling in the throat. Inhalation of high concentrations may cause lung oedema, but only after initial corrosive effects on the eyes and the upper respiratory tract have become manifest. See Notes.	Inhalation risk A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C. Effects of long-term or repeated exposure Repeated or prolonged contact with skin may cause dermatitis.

EXPOSURE & HEALTH EFFECTS

Routes of exposure
Serious local effects by all routes of exposure.

Effects of short-term exposure
The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. Contact of the vapour with the eyes may cause visual disturbances. Exposure could cause asphyxiation due to swelling in the throat. Inhalation of high concentrations may cause lung oedema, but only after initial corrosive effects on the eyes and the upper respiratory tract have become manifest. See Notes.

Inhalation risk
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C.

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis.

OCCUPATIONAL EXPOSURE LIMITS
TLV: 5 ppm as TWA; (skin)

ENVIRONMENT
The substance is harmful to aquatic organisms.

NOTES
The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. Isolate contaminated clothing by sealing in a bag or other container.

ADDITIONAL INFORMATION

EC Classification

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    See Also:
       Toxicological Abbreviations