ICSC 0287 - ISOPROPYL CHLOROFORMATE

ISOPROPYL CHLOROFORMATE	ICSC: 0287 (May 2003)
Isopropyl chlorocarbonate Chloroformic acid, isopropyl ester Carbonochloridic acid 1-methylethyl ester Isopropyl chloromethanate

CAS #: 108-23-6

UN #: 2407

EC Number: 203-563-2

	ACUTE HAZARDS	PREVENTION	FIRE FIGHTING
FIRE & EXPLOSION	Highly flammable. Gives off irritating or toxic fumes (or gases) in a fire. Vapour/air mixtures are explosive.	NO open flames, NO sparks and NO smoking. Closed system, ventilation, explosion-proof electrical equipment and lighting. Do NOT use compressed air for filling, discharging, or handling.	Use carbon dioxide, dry powder, alcohol-resistant foam, dry sand. In case of fire: keep drums, etc., cool by spraying with water. NO direct contact with water.

STRICT HYGIENE! IN ALL CASES CONSULT A DOCTOR!
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	Burning sensation. Cough. Laboured breathing. Shortness of breath. Sore throat. Symptoms may be delayed. See Notes.	Use ventilation, local exhaust or breathing protection.	Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.
Skin	Redness. Skin burns. Pain. Blisters.	Protective gloves. Protective clothing.	Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention .
Eyes	Watering of the eyes. Redness. Pain. Severe burns.	Wear safety goggles, face shield or eye protection in combination with breathing protection.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion	Abdominal pain. Burning sensation. Shock or collapse.	Do not eat, drink, or smoke during work.	Rinse mouth. Do NOT induce vomiting. Refer for medical attention .

SPILLAGE DISPOSAL	CLASSIFICATION & LABELLING
Personal protection: chemical protection suit including self-contained breathing apparatus. Ventilation. Remove all ignition sources. Do NOT wash away into sewer. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.	According to UN GHS Criteria Transportation UN Classification UN Hazard Class: 6.1; UN Subsidiary Risks: 3 and 8; UN Pack Group: I
STORAGE
Fireproof. Separated from strong oxidants and food and feedstuffs. Dry. Well closed.
PACKAGING
Do not transport with food and feedstuffs.

ISOPROPYL CHLOROFORMATE

ICSC: 0287

PHYSICAL & CHEMICAL INFORMATION
Physical State; Appearance COLOURLESS LIQUID WITH PUNGENT ODOUR. Physical dangers The vapour is heavier than air and may travel along the ground; distant ignition possible. Chemical dangers Decomposes on heating. This produces toxic and corrosive fumes including hydrogen chloride and phosgene. Reacts violently with strong oxidants. Reacts with water. This produces alcohol and hydrogen chloride (see ICSC 0163).	Formula: C₄H₇ClO₂ / (CH₃)₂CHOCOCl Molecular mass: 122.6 Boiling point: 104.6°C Relative density (water = 1): 1.08 Solubility in water: slow reaction Vapour pressure, kPa at 20°C: 3 Relative vapour density (air = 1): 4.2 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.1 Flash point: 20°C c.c. Auto-ignition temperature: >500°C Explosive limits, vol% in air: 4-15

PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS LIQUID WITH PUNGENT ODOUR.

Physical dangers
The vapour is heavier than air and may travel along the ground; distant ignition possible.

Chemical dangers
Decomposes on heating. This produces toxic and corrosive fumes including hydrogen chloride and phosgene. Reacts violently with strong oxidants. Reacts with water. This produces alcohol and hydrogen chloride (see ICSC 0163).

Formula: C₄H₇ClO₂ / (CH₃)₂CHOCOCl
Molecular mass: 122.6
Boiling point: 104.6°C
Relative density (water = 1): 1.08
Solubility in water: slow reaction
Vapour pressure, kPa at 20°C: 3
Relative vapour density (air = 1): 4.2
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.1
Flash point: 20°C c.c.
Auto-ignition temperature: >500°C
Explosive limits, vol% in air: 4-15

EXPOSURE & HEALTH EFFECTS
Routes of exposure The substance can be absorbed into the body by inhalation of its vapour and by ingestion. Effects of short-term exposure Lachrymation. The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. Inhalation of the vapour may cause lung oedema. See Notes. The effects may be delayed. Medical observation is indicated.	Inhalation risk No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20°C. Effects of long-term or repeated exposure

EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour and by ingestion.

Effects of short-term exposure
Lachrymation. The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. Inhalation of the vapour may cause lung oedema. See Notes. The effects may be delayed. Medical observation is indicated.

Inhalation risk
No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20°C.

Effects of long-term or repeated exposure

OCCUPATIONAL EXPOSURE LIMITS

ENVIRONMENT

NOTES
Health effects of exposure to the substance have not been investigated adequately. The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. Immediate administration of an appropriate inhalation therapy by a doctor, or by an authorized person, should be considered.

ADDITIONAL INFORMATION

EC Classification

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    See Also:
       Toxicological Abbreviations