ICSC 0200 - TETRAMETHYL LEAD

TETRAMETHYL LEAD	ICSC: 0200 (April 2005)
Tetramethyl plumbane

CAS #: 75-74-1

UN #: 1649

EC Number: 200-897-0

	ACUTE HAZARDS	PREVENTION	FIRE FIGHTING
FIRE & EXPLOSION	Flammable. Gives off irritating or toxic fumes (or gases) in a fire. Above 37.8°C explosive vapour/air mixtures may be formed.	NO open flames, NO sparks and NO smoking. Above 37.8°C use a closed system, ventilation and explosion-proof electrical equipment.	Use water spray, foam, powder, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water. Combat fire from a sheltered position.

STRICT HYGIENE! IN ALL CASES CONSULT A DOCTOR!
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	Convulsions. Dizziness. Headache. Nausea. Unconsciousness. Symptoms may be delayed. See Notes.	Use ventilation, local exhaust or breathing protection.	Fresh air, rest. Refer for medical attention.
Skin	MAY BE ABSORBED! Further see Inhalation.	Protective gloves. Protective clothing.	Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .
Eyes		Wear face shield or eye protection in combination with breathing protection.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion	Abdominal pain. Burning sensation. Diarrhoea. Dullness. Further see Inhalation.	Do not eat, drink, or smoke during work. Wash hands before eating.	Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer for medical attention .

SPILLAGE DISPOSAL	CLASSIFICATION & LABELLING
Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.	According to UN GHS Criteria Transportation UN Classification UN Hazard Class: 6.1; UN Pack Group: I
STORAGE
Fireproof. Separated from strong oxidants, strong acids and food and feedstuffs. Cool. Well closed. Store in an area without drain or sewer access.
PACKAGING
Unbreakable packaging. Put breakable packaging into closed unbreakable container. Do not transport with food and feedstuffs. Marine pollutant.

TETRAMETHYL LEAD

ICSC: 0200

PHYSICAL & CHEMICAL INFORMATION
Physical State; Appearance COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. Physical dangers The vapour is heavier than air. Chemical dangers May explode on heating above 90°C. Decomposes on burning. This produces toxic fumes including lead and lead oxides. Reacts violently with strong oxidants. Reacts with strong acids. Reacts violently with nitric acid. Attacks rubber.	Formula: Pb(CH₃)₄ / C₄H₁₂Pb Molecular mass: 267.4 Boiling point at 1.33kPa: 110°C Melting point: -27.5°C Relative density (water = 1): 2.0 Solubility in water: none Vapour pressure, kPa at 20°C: 3.0 Relative vapour density (air = 1): 6.5 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.23 Flash point: 37.8°C c.c. Auto-ignition temperature: 254°C Explosive limits, vol% in air: 1.8-? Octanol/water partition coefficient as log Pow: 6.2

PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR.

Physical dangers
The vapour is heavier than air.

Chemical dangers
May explode on heating above 90°C. Decomposes on burning. This produces toxic fumes including lead and lead oxides. Reacts violently with strong oxidants. Reacts with strong acids. Reacts violently with nitric acid. Attacks rubber.

Formula: Pb(CH₃)₄ / C₄H₁₂Pb
Molecular mass: 267.4
Boiling point at 1.33kPa: 110°C
Melting point: -27.5°C
Relative density (water = 1): 2.0
Solubility in water: none
Vapour pressure, kPa at 20°C: 3.0
Relative vapour density (air = 1): 6.5
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.23
Flash point: 37.8°C c.c.
Auto-ignition temperature: 254°C
Explosive limits, vol% in air: 1.8-?
Octanol/water partition coefficient as log Pow: 6.2

EXPOSURE & HEALTH EFFECTS
Routes of exposure The substance can be absorbed into the body by inhalation, through the skin and by ingestion. Effects of short-term exposure The substance may cause effects on the central nervous system. This may result in brain disorders. The effects may be delayed. Exposure could cause death. Medical observation is indicated.	Inhalation risk A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C. Effects of long-term or repeated exposure

EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion.

Effects of short-term exposure
The substance may cause effects on the central nervous system. This may result in brain disorders. The effects may be delayed. Exposure could cause death. Medical observation is indicated.

Inhalation risk
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C.

Effects of long-term or repeated exposure

OCCUPATIONAL EXPOSURE LIMITS
TLV: 0.15 mg/m³, as TWA; (skin). MAK: (as Pb): 0.05 mg/m³, ppm; peak limitation category: II(2); skin absorption (H); pregnancy risk group: B

ENVIRONMENT
The substance is very toxic to aquatic organisms. Bioaccumulation of this chemical may occur along the food chain, for example in molluscs and fish.

NOTES
Commercial products are impure, coloured red, orange or blue, with added stabilizer (1,2-dichloroethane, toluene). Depending on the degree of exposure, periodic medical examination is suggested. The relation between odour and the occupational exposure limit cannot be indicated. Do NOT take working clothes home.

ADDITIONAL INFORMATION

EC Classification
Symbol: T+, N; R: 61-26/27/28-33-62-50/53; S: 53-45-60-61; Note: A, E, 1

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    See Also:
       Toxicological Abbreviations