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Summary of Evaluations Performed by the
Joint FAO/WHO Expert Committee on Food Additives

1,3-DICHLORO-2-PROPANOL
Functional class: CONTAMINANT
Latest evaluation: 2001
Comments: Establishment of a tolerable intake was considered to be inappropriate because of the nature of toxicity (tumorogenic in various organs in rats and the contaminant can interact with chromosomes and/or DNA). The Committee noted that the dose that caused tumours in rats (19 mg/kg bw per day) was about 20000 times the highest estimated intake of 1,3-dichloro-2-propanol by consumers of soya sauce (1 µg/kg bw per day).
Report: TRS 909-JECFA 57/118
Tox monograph: FAS 48-JECFA 57/433
Previous status: 1993, TRS 837-JECFA 41/30,32, FAS 32-JECFA 41/267. LEVELS IN HYDROLYSED VEGETABLE PROTEINS SHOULD BE REDUCED AS FAR AS TECHNICALLY POSSIBLE
 
30 Jan 03    





    See Also:
       Toxicological Abbreviations
       1,3-dichloro-2-propanol (ICSC)
       1,3-dichloro-2-propanol (JECFA Food Additives Series 48)