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Summary of Evaluations Performed by the
Joint FAO/WHO Expert Committee on Food Additives

L-HISTIDINE
FEMA No.: 3694
JECFA No.: 1431
Chemical names: L-HISTIDINE
Synonyms: L-ALPHA-AMINO-4(OR 5)-IMIDAZOLEPROPIONIC ACID; 2-AMINO-3(4-IMIDASYL)PROPIONIC ACID
Functional class: FLAVOURING AGENT
Latest evaluation: 2004
ADI: ACCEPTABLE
Comments: No safety concern at current levels of intake when used as a flavouring agent. Not evaluated using the Procedure for the Safety Evaluation of Flavouring Agents; the substance is a macronutrient and a normal component of protein and, as such, human exposure through food is orders of magnitude higher than the anticipated level of exposure from use as a flavouring agent.
Report: TRS 928-JECFA 63/98
Specifications: COMPENDIUM ADDENDUM 12/FNP 52 Add. 12/90
Tox monograph: FAS 54-JECFA 63/435
 
28 Jan 06    




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       Toxicological Abbreviations