ICSC 1143 - CRUFOMATE(OBSOLETE)

CRUFOMATE (OBSOLETE)	ICSC: 1143 (October 1995)
4-tert-Butyl-2-chlorophenyl methyl methylphosphoramidate Amidophos

CAS #: 299-86-5

UN #: 2783

EC Number: 206-083-1

	ACUTE HAZARDS	PREVENTION	FIRE FIGHTING
FIRE & EXPLOSION	Combustible. Liquid formulations containing organic solvents may be flammable.	NO open flames.	Use water spray, powder.

AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN!
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	Dizziness. Sweating. Laboured breathing. Nausea. Unconsciousness. Vomiting. Pupillary constriction, muscle cramp, excessive salivation.	Avoid inhalation of dust and mist. Use local exhaust or breathing protection.	Fresh air, rest. Refer for medical attention.
Skin	MAY BE ABSORBED! Redness. Further see Inhalation.	Protective gloves. Protective clothing.	Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .
Eyes	Redness. Pain.	Wear face shield or eye protection in combination with breathing protection if powder.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion	Abdominal cramps. Diarrhoea. Nausea. Vomiting. Pupillary constriction. Muscle cramps. Excessive salivation.	Do not eat, drink, or smoke during work. Wash hands before eating.	Refer for medical attention .

SPILLAGE DISPOSAL	CLASSIFICATION & LABELLING
Personal protection: complete protective clothing including self-contained breathing apparatus. Sweep spilled substance into sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. Do NOT wash away into sewer.	According to UN GHS Criteria Transportation UN Classification UN Hazard Class: 6.1; UN Pack Group: III
STORAGE
Separated from strong bases, strong acids and food and feedstuffs. Well closed. Keep in a well-ventilated room.
PACKAGING
Do not transport with food and feedstuffs.

CRUFOMATE (OBSOLETE)

ICSC: 1143

PHYSICAL & CHEMICAL INFORMATION
Physical State; Appearance WHITE CRYSTALS. Physical dangers No data. Chemical dangers Decomposes on heating. This produces toxic and corrosive fumes including hydrogen chloride, nitrogen oxides and phosphorus oxides. Reacts with strong acids and strong bases.	Formula: C₁₂H₁₉ClNO₃P Molecular mass: 291.7 Decomposes at 60-65°C Relative density (water = 1): 1.5 Solubility in water: none Vapour pressure, Pa at 25°C: 0.106

PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
WHITE CRYSTALS.

Physical dangers
No data.

Chemical dangers
Decomposes on heating. This produces toxic and corrosive fumes including hydrogen chloride, nitrogen oxides and phosphorus oxides. Reacts with strong acids and strong bases.

Formula: C₁₂H₁₉ClNO₃P
Molecular mass: 291.7
Decomposes at 60-65°C
Relative density (water = 1): 1.5
Solubility in water: none
Vapour pressure, Pa at 25°C: 0.106

EXPOSURE & HEALTH EFFECTS
Routes of exposure The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. Effects of short-term exposure The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the nervous system. This may result in convulsions and respiratory failure. Cholinesterase inhibition. The effects may be delayed. Medical observation is indicated.	Inhalation risk Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying or when dispersed, especially if powdered. Effects of long-term or repeated exposure

EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion.

Effects of short-term exposure
The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the nervous system. This may result in convulsions and respiratory failure. Cholinesterase inhibition. The effects may be delayed. Medical observation is indicated.

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying or when dispersed, especially if powdered.

Effects of long-term or repeated exposure

OCCUPATIONAL EXPOSURE LIMITS
TLV: 5 mg/m³, as TWA; A4 (not classifiable as a human carcinogen); BEI issued

ENVIRONMENT
The substance is very toxic to aquatic organisms. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal.

NOTES
Depending on the degree of exposure, periodic medical examination is suggested. Carrier solvents used in commercial formulations may change physical and toxicological properties. Do NOT take working clothes home.

ADDITIONAL INFORMATION

EC Classification
Symbol: Xn, N; R: 21/22-50/53; S: (2)-36/37-60-61

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    See Also:
       Toxicological Abbreviations
       Crufomate (FAO/PL:1968/M/9/1)
       Crufomate (WHO Pesticide Residues Series 2)