CYCLOPHOSPHAMIDE (ANHYDROUS) | ICSC: 0689 (April 2017) |
2-Bis(2-chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide 2-H-1,3,2-Oxazaphosphorinane |
CAS #: 50-18-0 |
UN #: 3464 |
EC Number: 200-015-4 |
ACUTE HAZARDS | PREVENTION | FIRE FIGHTING | |
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FIRE & EXPLOSION | Combustible. Gives off irritating or toxic fumes (or gases) in a fire. | NO open flames. | Use water spray, powder, foam, carbon dioxide. |
AVOID ALL CONTACT! AVOID EXPOSURE OF BREASTFEEDING WOMEN! | |||
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SYMPTOMS | PREVENTION | FIRST AID | |
Inhalation | Use closed system and ventilation. | Fresh air, rest. | |
Skin | Protective gloves. Protective clothing. | Remove contaminated clothes. Rinse skin with plenty of water or shower. | |
Eyes | Wear face shield or eye protection in combination with breathing protection. | Rinse with plenty of water for several minutes (remove contact lenses if easily possible). | |
Ingestion | Diarrhoea. Dizziness. Nausea. Vomiting. Abdominal pain. | Do not eat, drink, or smoke during work. Wash hands before eating. | Rinse mouth. Refer for medical attention . |
SPILLAGE DISPOSAL | CLASSIFICATION & LABELLING |
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Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into covered sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. |
According to UN GHS Criteria DANGER
Toxic if swallowedMay cause genetic defects May cause cancer May damage fertility or the unborn child May cause harm to breast-fed children May cause damage to blood, bone marrow and lungs through prolonged or repeated exposure Transportation |
STORAGE | |
Separated from food and feedstuffs. Dry. Keep in the dark. Well closed. See Chemical Dangers. | |
PACKAGING | |
CYCLOPHOSPHAMIDE (ANHYDROUS) | ICSC: 0689 |
PHYSICAL & CHEMICAL INFORMATION | |
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Physical State; Appearance
Physical dangers
Chemical dangers
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Formula: C7H15Cl2N2O2P |
EXPOSURE & HEALTH EFFECTS | |
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Routes of exposure
Effects of short-term exposure
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Inhalation risk
Effects of long-term or repeated exposure
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OCCUPATIONAL EXPOSURE LIMITS |
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ENVIRONMENT |
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Environmental effects from the substance have not been investigated adequately. |
NOTES |
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CAS No. for monohydrate is 6055-19-2. Depending on the degree of exposure, periodic medical examination is suggested. Do NOT take working clothes home. |
ADDITIONAL INFORMATION | ||
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EC Classification |
All rights reserved. The published material is being distributed without warranty of any kind, either expressed or implied. Neither ILO nor WHO nor the European Commission shall be responsible for the interpretation and use of the information contained in this material. | |
See Also: Toxicological Abbreviations Cyclophosphamide (IARC Summary & Evaluation, Supplement7, 1987) Cyclophosphamide (IARC Summary & Evaluation, Volume 9, 1975) Cyclophosphamide (IARC Summary & Evaluation, Volume 26, 1981)