VOL.: 30 (1983) (p. 73)
Chem. Abstr. Name: Benzeneacetic acid, 4-chloro-a-(4-chlorophenyl)- a-hydroxy-, ethyl ester
Although no adverse effect was observed on reproduction in a three-generation study of rats, the teratogenic potential of chlorobenzilate has not been fully determined.
Chlorobenzilate was not mutagenic to Salmonella typhimurium with or without exogenous metabolic activation. Data from studies on other organisms were considered insufficient for evaluation, and no overall evaluation of the mutagenicity of chlorobenzilate could be made.
No data were available to evaluate the teratogenic or chromosomal effects of chlorobenzilate in humans.
No case report or epidemiological study of the carcinogenicity of chlorobenzilate alone was available to the Working Group. (See, however, the section 'Cancer Epidemiology of Pesticide Manufacturers, Formulators and Users', in this volume.)
The available data are insufficient to evaluate the carcinogenicity of chlorobenzilate to humans.
For definition of the italicized terms, see Preamble Evaluation.
Previous evaluation: Vol. 5 (1974)
Subsequent evaluation: Suppl. 7 (1987) (p. 60: Group 3)
See Also: Toxicological Abbreviations Chlorobenzilate (ICSC) Chlorobenzilate (FAO Meeting Report PL/1965/10/1) Chlorobenzilate (FAO/PL:1968/M/9/1) Chlorobenzilate (WHO Pesticide Residues Series 2) Chlorobenzilate (WHO Pesticide Residues Series 5) Chlorobenzilate (Pesticide residues in food: 1977 evaluations) Chlorobenzilate (Pesticide residues in food: 1980 evaluations) Chlorobenzilate (IARC Summary & Evaluation, Volume 5, 1974)