International Agency for Research on Cancer (IARC) - Summaries & Evaluations


VOL.: 13 (1977) (p. 47)

CAS No.: 54-05-7
Chem. Abstr. Name: N4-(7-Chloro-4-quinolinyl)-N1, N1-diethyl-1,4-pentanediamine

5. Summary of Data Reported and Evaluation

5.1 Animal data

The negative results obtained in the only available study in rats given chloroquine by oral administration did not form an adequate basis on which to make an evaluation of the carcinogenicity of this compound.

N.B. - The Working Group was aware of an on-going carcinogenicity study in mice (IARC, 1976).

5.2 Human data

No case reports or epidemiological studies were available to the Working Group.

Subsequent evaluation: Suppl. 7 (1987) (p. 60: Group 3)

For definition of Groups, see Preamble Evaluation.


Last updated: 25 March 1998

    See Also:
       Toxicological Abbreviations
       Chloroquine (PIM 123)