International Agency for Research on Cancer (IARC) - Summaries & Evaluations


VOL.: 12 (1976) (p. 151)

CAS No.: 598-55-0
Chem. Abstr. Name: Carbamic acid, methyl ester

5. Summary of Data Reported and Evaluation

5.1 Animal carcinogenicity data

Methyl carbamate has been tested for skin and lung tumour induction in mice by subcutaneous and intraperitoneal administration and by skin application. Although no significant carcinogenic effect was observed, no evaluation of carcinogenicity can be made due to the short duration of these experiments. It must be pointed out that in parallel experiments the related chemical, urethane, was carcinogenic (IARC, 1974 - Volume 7).

5.2 Human carcinogenicity data

No case reports or epidemiological studies were available to the Working Group.

Subsequent evaluation: Suppl. 7 (1987) (p. 66: Group 3)

For definition of Groups, see Preamble Evaluation.


Last updated: 25 March 1998

    See Also:
       Toxicological Abbreviations