Coumarin (IARC Summary & Evaluation, Volume 10, 1976)

International Agency for Research on Cancer (IARC) - Summaries & Evaluations

COUMARIN

VOL.: 10 (1976) (p. 113)

CAS No.: 91-64-5
Chem. Abstr. Name: 2H-1-Benzopyran-2-one

5. Summary of Data Reported and Evaluation

5.1 Animal carcinogenicity data

Coumarin is carcinogenic in rats following its oral administration, the only species and route of administration tested; it produced bile duct carcinomas.

5.2 Human carcinogenicity data

No case reports or epidemiological studies were available to the Working Group.

Subsequent evaluation: Suppl. 7 (1987) (p. 61: Group 3); Vol. 77 (2000)

For definition of Groups, see Preamble Evaluation.

Synonyms for Coumarin

1,2-Benzopyrone
cis-o-Coumarinic acid lactone
Coumarinic anhydride
Cumarin
2-Oxo-2H-1-benzopyran
Tonka bean camphor

Last updated: 22 March 1998





























    See Also:
       Toxicological Abbreviations
       Coumarin (ICSC)
       Coumarin (WHO Food Additives Series 16)
       Coumarin  (IARC Summary & Evaluation, Volume 77, 2000)