International Agency for Research on Cancer (IARC) - Summaries & Evaluations


VOL.: 8 (1975) (p. 199)

CAS No.: 3564-09-8
Chem. Abstr. Name: 3-Hydroxy-4-[(2,4,5-trimethylphenyl)azo]-2,7-naphthalenedisulfonic acid, disodium salt

5. Summary of Data Reported and Evaluation

5.1 Animal carcinogenicity data

Ponceau 3R is carcinogenic in rats following its oral administration, producing liver-cell tumours. It also produced bladder tumours in mice following its implantation in the urinary bladder. The oral study in mice was considered inadequate for evaluation.

5.2 Human carcinogenicity data

No case reports or epidemiological studies were available to the Working Group.

Subsequent evaluation: Suppl. 7 (1987) (p. 70: Group 2B)

For definition of Groups, see Preamble Evaluation.


  • A.F. red No. 1
  • C.I. Food Red 6
  • C.I. Food Red 6 disodium salt
  • Disodium 3-hydroxy-4-[(2,4,5-trimethylphenyl)azo]-2,7-naphthalenedisulfonate
  • Dolkwal ponceau 3R
  • Ext. D and C red No. 15
  • External D and C red No. 15
  • Extract D and C red No. 15
  • FD and C red No. 1
  • 3-Hydroxy-4-[(2,4,5-trimethylphenyl)azo]-2,7-naphthalenedisulfonic acid, disodium salt
  • Maple ponceau 3R
  • Ponceau 3R lake
  • Ponceau RN
  • Ponceau 3R sodium salt
  • Sodium cumeneazo-b-naphthol disulfonate
  • Usacert red No. 1

  • Last updated: 21 March 1998
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           Toxicological Abbreviations