International Agency for Research on Cancer (IARC) - Summaries & Evaluations


VOL.: 3 (1973) (p. 241)

5. Summary of Data Reported and Evaluation

5.1 Animal carcinogenicity data

Benz(c)acridine produced skin tumours in mice treated topically and bladder tumours in rats following local paraffin wax pellet implantation. It has not been tested in other species or by other routes.

5.2 Human carcinogenicity data

No case reports or epidemiological studies on the significance of benz(c)acridine exposure to man are available. However, coal-tar and other materials which are known to be carcinogenic to man may contain benz(c)acridine. The substance has also been detected in other environmental situations. The possible contribution of heterocyclic compounds from some environmental sources to the overall carcinogenic risk to man is discussed in the General Remarks.

Subsequent evaluation: Vol. 32 (1983); Suppl. 7 (1987) (p. 58: Group 3)

For definition of Groups, see Preamble Evaluation.

Last updated: 16 March 1998

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       Toxicological Abbreviations