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    PESTICIDE RESIDUES IN FOOD - 1980


    Sponsored jointly by FAO and WHO






    EVALUATIONS 1980





    Joint meeting of the
    FAO Panel of Experts on Pesticide Residues
    in Food and the Environment
    and the
    WHO Expert Group on Pesticide Residues
    Rome, 6-15 October 1980




    IPRODIONE

    Explanation

    Iprodione was evaluated at the 1977 JMPR.  An ADI has been
    established and maximum residue levels were estimated on various
    commodities suitable for establishing maximum residue limits.

    Additional information on residue levels in grain crops and in
    products of animal origin was listed as desirable.  Also
    information was sought on the effect of processing and cooking.


    RESIDUES RESULTING FROM SUPERVISED TRIALS

    The requested information was not available at this Meeting. 
    However some data were submitted on residues from supervised trials
    on kiwi fruit carried out in New Zealand in which iprodione was
    used according to good agricultural practice: about 5 applications
    were made at the rate of 37.5 g ai/100 l with a pre-harvest
    interval of 3-4 days.

    The residue levels found are shown in Table 1; the residues of the
    metabolites 30228 RP and 32490 RP (see Evaluations of JMPR 1977)
    together did not exceed 0.2 mg/kg at all treatment rates.  The
    recovery of the parent compound was 91% and of the metabolites
    82-84%. A GLC method of analysis was used.



        TABLE 1.  Residues of iprodione in kiwi fruit

                                                                                                                           
    Year       Dosage rate                                 Residues (mg/kg) mean value and range
                  mg/kg                                              Days after treatment
                                  0              1               3/4             7/8             14/15            22/23
                                                                                                                           

    1979/80       3.75                      3.0(3.3-4.1)    4.5(4.3-4.7)                    0.23(0.2-0.25)     1.8(1.7-1.9)
    1979/80       3.75       3.5(3.3-3.7)   3.9(3.7-4.0)    3.4(3.4-4.0)     2.1(2.1-2.2)   0.12(0.11-0.13)
    1979/80       3.75       3.2(3.1-3.3)   2.6(2.6-2.6)    2.4(2.3-2.5)                    1.7(1.7-1.7)      0.92(0.90-0.94)
                                                                                                                           
    

    From the data summarised in Table 1 the meeting was able to estimate
    the maximum residue levels that are likely to occur on kiwi fruit when
    iprodione is used in practice.


    RECOMMENDATIONS

    The Meeting concludes that the maximum residue level listed below is
    suitable for establishing a maximum residue limit.  The level refers
    to parent compound only.

                                                                       
    Commodity     Estimated maximum   Interval between last application
                  residue levels      and harvest on which the max.
                  mg/kg               residue level is based
                                                                       

    Kiwi fruit         5                        3-4
                                                                       

    FURTHER WORK OR INFORMATION

    Desirable

    The information listed in the 1977 Evaluations page 138.

    


    See Also:
       Toxicological Abbreviations
       Iprodione (Pesticide residues in food: 1977 evaluations)
       Iprodione (Pesticide residues in food: 1992 evaluations Part II Toxicology)
       Iprodione (Pesticide residues in food: 1995 evaluations Part II Toxicological & Environmental)