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    Annex 1

    RECOMMENDATIONS CONCERNING ACCEPTABLE DAILY INTAKES AND RESIDUE
    LIMITS MADE AT THE 1974 MEETING

    
    These recommendations are additional to, or amend, those recorded in Annex 1 of the report of the 1972 Meeting (FAO/WHO, 1973a) as well as
    those recorded in Annex 1 of the report of the 1973 Meeting (FAO/WHO, 1974a).

    Temporary recommendations are denoted by superscripts a, b, or, c, indicating that further work is to be made available not later than
    30 June in the year 1975, 1976, or 1977 respectively.

    Further explanatory notes are given at the end of this table (see page 30).

                                                                                                                                               
                         Maximum
                         acceptable                                           Residue limits (mg/kg)
                         daily                                                Tolerances
                         intake                                               (practical    Guideline
    Pesticides and       (mg/kg                                               limits        levels 2
    references           body       Commodity                                 indicated                    Remarks
                         weight)                                              as (P))
                                                                                                                                               

                                                                                                           See also dieldrin.
    aldfin               0.0001
    1967b, 1968b

    amitrole             0.00003    Raw agricultural commodities              0.02 *                       Conditional ADI : uses of amitrole
    1975b                           of plant origin                                                        should be restricted to those where
                                                                                                           food rescues would be unlikely to
                                                                                                           occur.

    binapacryl           0.0025     Cherries                                  0.5
    1970b, 1975b

    captafol             0.05 b     Apricots                                  15 b                         Figures relate only to parent
    compound.
    1970b, 1974b,                   Plums                                     10 b
    1975b

    Annex 1 (Cont'd.)

                                                                                                                                               
                         Maximum
                         acceptable                                           Residue limits (mg/kg)
                         daily                                                Tolerances
                         intake                                               (practical    Guideline
    Pesticides and       (mg/kg                                               limits        levels 2
    references           body       Commodity                                 indicated                    Remarks
                         weight)                                              as (P))
                                                                                                                                               

    chinomethionat       0.003 c    Papayas (whole fruit)                     5.0 c
    (oxythioquinox)                 Apples citrus fruits                      0.5 c
    1969b, 1975b                    Almond (kernels), avocado, raw
                                     cereals, cucumbers, currants
                                     (black, red, white), grapes,
                                     gherkins, gooseberries,
                                     papaya (pulp)                            0.1 c
                                    Macadamia nut (kernels)                   0.02*
                                    Meat                                      0.05*
                                    Milk                                      0.01*

    chlorothalonil       0.03 c     Peaches                                   30 c
    1975b                           Currants (black, red, white)              25 c
                                    Celery                                    15 c
                                    Blackberries, cherries,
                                     chicory sprouts, collards,
                                     endive, kale, lettuce (head),
                                     raspberries, peppers                     10 c
                                    Beans (green including pod), broccoli,
                                     Brussels sprouts, cabbage,
                                     cauliflower, cranberries, cucumbers,
                                     melons, onions, oranges, pumpkins,
                                     squash, tomatoes                         5 c
                                    Carrots, sweet corn, sugar beets          1 c
                                    Lima beans, peanuts (whole)               0.5 c

                                    Peanuts (kernels), potatoes               0.1 c

    Annex 1 (Cont'd.)

                                                                                                                                               
                         Maximum
                         acceptable                                           Residue limits (mg/kg)
                         daily                                                Tolerances
                         intake                                               (practical    Guideline
    Pesticides and       (mg/kg                                               limits        levels 2
    references           body       Commodity                                 indicated                    Remarks
                         weight)                                              as (P))
                                                                                                                                               

    chlorpyrifos         0.0015     Citrus fruit (whole)                      0.3
    1973b, 1975b

    cyhexatin            0.007 c    Apples, pears,                                                         Tolerances are expressed as the parent
    1971b, 1974b.                    tomatoes                                 2 c                          compound excluding organic degradation
    1975b                           Gherkins                                  1 c                          products and inorganic tin.
                                    Cucumbers, melons, bell peppers -         0.5 c                        Formerly listed as tricyclohexy
                                     (glasshouse use only)                                                     hydroxide or as tricyclohexyl
                                                                                                               hydro-oxystannate.       

    2,4-D                0.3        Citrus fruit                              2
    1971b, 1972b,                   Potatoes                                  0.2
    1975b                           Milk and milk products (fat basis)        0.05 * (P)

    dichlofluanid        0.3 c      Currants (red, black, white), grapes,                                  Recommendations apply to the parent
    1970b, 1975b                     raspberries                              15 c                         compound.
                                    Lettuce, strawberries                     10 c
                                    Apples, cucumbers, peaches, peers         5 c
                                    Tomatoes beans (green with pod),
                                     cherries                                 2 c

    2,6-dichlaro-4-      0.03 c     Cherries, peaches                         15 c
    nitrobenzenamine                Apricots, carrots, grapes, lettuce,
    (dichloran)                      plums, raspberries, strawberries         10 c
    1975b                           Blackberries, currants (red, white,
                                     black)                                   5 c
                                    Beans (French)                            2
                                    Gherkins, tomatoes                        0.5

    Annex 1 (Cont'd.)

                                                                                                                                               
                         Maximum
                         acceptable                                           Residue limits (mg/kg)
                         daily                                                Tolerances
                         intake                                               (practical    Guideline
    Pesticides and       (mg/kg                                               limits        levels 2
    references           body       Commodity                                 indicated                    Remarks
                         weight)                                              as (P))
                                                                                                                                               

    dichlorvos           0.004      Vegetables (except lettuce)               0.5                          See FAO/WHO, 1973a, Annex 1,
    1967b, 1968b,                                                                                          Remarks.
    1970b, 1971b,
    1975b

    dicofol              0.025      Fruits (except strawberries)              5
    1969b, 1971b,                   Vegetables (except cucumbers,
    1975b                            gherkins, tomatoes)                      5
                                    Cucumbers, gherkins                       2
                                    Strawberries, tomatoes                    1

    dieldrin             0.0001     Fruits (other than citrus)                0.1 a
    1967b, 1968b,
    1969b, 1970b, 1971b

    dinocap             No ADI      Apples, apricots, blackberries,
    1970b, 1975b                    boysenberries, cantaloupes,
                                    cucumbers, grapes, honeydew
                                    melons, muskmelons, peaches,
                                    peers, pumpkins, raspberries,
                                    squash, strawberries                                    0.1 *

    dithiocarbamates,    0.005 c                                                                           Revised temporary ADI, which applies
    dimethyl                                                                                               to the parent compounds or to the
    (ferbam, thiram,                                                                                       sum of residues of all compounds
    and ziram)                                                                                             present.
    1965b, 1968b,
    1971b, 1975a

    Annex 1 (Cont'd.)

                                                                                                                                               
                         Maximum
                         acceptable                                           Residue limits (mg/kg)
                         daily                                                Tolerances
                         intake                                               (practical    Guideline
    Pesticides and       (mg/kg                                               limits        levels 2
    references           body       Commodity                                 indicated                    Remarks
                         weight)                                              as (P))
                                                                                                                                               

    dithiocarbamates,    0.005 c                                                                           Revised temporary ADI, which applies
    ethylene                                                                                               to the parent compounds or to the
    bis-(mancozeb, maneb,                                                                                  sum of residues of all compounds
    and zineb, including                                                                                   present.
    zineb derived from
    nabam plus zinc
    sulfate)
    1965b, 1968b,
    1971b, 1975a

    dodine               0.01 b     Grapes, peaches, strawberries             5 b
    1975b                           Apples, cherries, pears                   2 b

    endosulfan           0.0075
    1968b, 1969,                    Fruits, vegetables (except carrots,
    1972b, 1975b                     potatoes, sweet potatoes, onions)        2
                                    Cottonseed                                1
                                    Cottonseed oil (crude)                    0.5
                                    Milk and milk products (fat basis)        0.5 (P)
                                    Carrots, potatoes, sweet potatoes,
                                     bulb onions                              0.2
                                    Fat of meat                               0.2 (P)
                                    Rice (in husk)                            0.1

    endrin               0.0002     Fat of meat                               0.1 (P)
    1965b, 1971b,
    1975b

    Annex 1 (Cont'd.)

                                                                                                                                               
                         Maximum
                         acceptable                                           Residue limits (mg/kg)
                         daily                                                Tolerances
                         intake                                               (practical    Guideline
    Pesticides and       (mg/kg                                               limits        levels 2
    references           body       Commodity                                 indicated                    Remarks
                         weight)                                              as (P))
                                                                                                                                               

    fenamiphos           0.0006     Potatoes, tomatoes                        0.2 c                        Tolerances refer to fenamiphos and to
    1975b                           Bananas, coffee beans (green and                                       its sulfoxide and sulfone, expressed as
                                     roasted), grapes, sweet potatoes         0.1                          fenamiphos. Tolerances for potatoes
                                    Broccoli, Brussels sprouts, cabbage,                                   and tomatoes are temporary.
                                     carrots, cauliflower, citrus fruits.
                                     cottonseed, melons, peanuts
                                     (kernels), pineaple, soybeans
                                     (dried), sugar beets                     0.05 *

    fenitrothion         0.005      Wheat bran                                20                           Revised ADI.
    1970b, 1975b                    Wheat                                     10                           Tolerances refer to fenitrothion and its
                                    Wheat flour (wholemeal)                    5                           oxygen analogue, expressed as
                                    Peaches                                    2                           fenitrothion.
                                    Wheat flour (white)                        1
                                    Apples, cabbage, red cabbage,
                                     cherries, grapes, lettuce, rice
                                     (in husk), peas, strawberries, tea
                                     (green, dry), tomatoes                   0.5
                                    Bread (white), leeks, oranges,
                                     radishes                                 0.2
                                    Cauliflower, cocoa beans, eggplant,
                                     pears, peppers, rice (polished),
                                     soybeans (dry)                           0.1
                                    Cucumbers, meat, fat of meat, milk,
                                     milk products, onions, potatoes          0.05 *

    ferbam               0.005 c                                                                           Revised temporary ADI.
    1965b, 1968b,
    1971b, 1975a

    Annex 1 (Cont'd.)

                                                                                                                                               
                         Maximum
                         acceptable                                           Residue limits (mg/kg)
                         daily                                                Tolerances
                         intake                                               (practical    Guideline
    Pesticides and       (mg/kg                                               limits        levels 2
    references           body       Commodity                                 indicated                    Remarks
                         weight)                                              as (P))
                                                                                                                                               

    hexachlorobenzene    0.0006                                                                            Conditional ADI.
    1970b, 1974a, b,                                                                                       Previous residue limits (1974a)
    1975a, b                                                                                               confirmed.

                                    Broccoli, Brussels sprouts, cabbage,
    leptophos           No ADI       lettuce, tomatoes                                      2              Guideline levels refer to leptophos and
    1975b                           Cottonseed oil (crude)                                  1              to its oxygen analogue and
                                    Cottonseed, cottonseed meal                             0.2            desbromoleptophos, expressed as leptophos.
                                    Potatoes                                                0.1
                                    Maize : field corn (kernels), sweet
                                            corn (cobs and kernels,
                                            husks and silks removed)                        0.05

    mancozeb             0.005 c    Beans (with pod)                          3 c (0.1)                    Revised temporary ADI.
    1968b, 1971b,                   Apples,* pears                            2 c (0.02)                   Residue limits should be based on and
    1975a                           Celery, lettuce                           2 c (0.01) *                 determined by measurement of the
                                    Tomatoes                                  1 c (0.05)                   ethylenediamine moiety, and of ethylen
                                    Carrots maize : sweet corn (cob and                                    ethiourea (ETU). Limits for ETU are
                                     kernels, husks and silks removed)        0.2 c (0.01 *                also recommended and appear in
                                    Potatoes banana (pulp)                    0.05 c (0.01) *              brackets. Neither limit should be
                                                                                                           exceeded in a given sample.

    maneb                0.005 c                                                                           Revised temporary ADI.
    1965b, 1968b,
    1971b, 1975a

    nabam                0.005 c                                                                           Revised temporary ADI.
    1965b, 1968b,
    1971b, 1975a

    Annex 1 (Cont'd.)

                                                                                                                                               
                         Maximum
                         acceptable                                           Residue limits (mg/kg)
                         daily                                                Tolerances
                         intake                                               (practical    Guideline
    Pesticides and       (mg/kg                                               limits        levels 2
    references           body       Commodity                                 indicated                    Remarks
                         weight)                                              as (P))
                                                                                                                                               

    oxythioquinox -
    See chinomethionat

    phosphamidon         0.001      Beans, broccoli, Brussels sprouts,                                     Tolerances are for the sum of
    1965b, 1967b,                     cabbage, carrots, celeriac, green                                    phosphamidon and its desethyl derivative,
    1969b, 1970b,                     peppers, peas, spinach, cherries,                                    expressed as phosphamidon.
    1973b, 1975b,                    peaches, plums, strawberries             0.2

    pirimiphos methyl    0.005 b    Bran (wheat, rice)                        20 h
    1975b                           Wheat, rye, rice (in husk)                10 b
                                    Barley, maize, oats                        7 b
                                    Wholemeal flour (wheat, rye)               5 b

                                    Rice (hulled), wheat flour (white)        2 b
                                    Bread (wholemeal), rice (polished)        1 b
                                    Bread (white)                             0.5 b
                                    Meat, milk, eggs                          0.05 * b

    pyrethrins           0.04       Peanut kernels                            1                            Previously recommended
    1967b                                                                                                  tolerances confirmed
                                                                                                           and no longer temporary.

    quintozene           0.001 a    See remarks                                                            The temporary tolerance for
    1970b, 1974b,                                                                                          mushrooms, recommended in 1969
    1975b                                                                                                  and 1973, is withdrawn.

    tecnazene           No ADI
    1975b

    Annex 1 (Cont'd.)

                                                                                                                                               
                         Maximum
                         acceptable                                           Residue limits (mg/kg)
                         daily                                                Tolerances
                         intake                                               (practical    Guideline
    Pesticides and       (mg/kg                                               limits        levels 2
    references           body       Commodity                                 indicated                    Remarks
                         weight)                                              as (P))
                                                                                                                                               

    thiram               0.005 c                                                                           Revised temporary ADI.
    1965b, 1968b,
    1971b, 1975a

    zineb                0.005 c                                                                           Revised temporary ADI.
    1965b, 1968b,
    1971b, 1975a

    ziram                0.005 c                                                                           Revised temporary ADI.
    1965b, 1968b,
    1971b, 1975a
                                                                                                                                               

    1. References are to FAO/WHO publications (see list of references on p.23). Dates of publication refer to the first complete or completely
    revised monograph or to important mentions of the compound in a report. Where a monograph has been completely revised mention is not necessarily
    made of any earlier one.

    2. Guideline levels are included to assist administering authorities, even though ADIs have not been established for the individual products,
    or temporary ADIs established at an earlier date have been withdrawn. The levels recommended are those that need not be exceeded if good
    practices are followed.

    * Level at or about the limit of determination.
       

    ANNEX II

    REFERENCES

    FAO/WHO. (1958) Procedures for the testing of intentional food
    additives to establish their safety for use. Second report of the
    Joint FAO/WHO Expert Committee on Food Additives. FAO Nutrition
    Meetings Report Series No. 17; Wld Hlth Org. techn. Rep. Ser., 144.

    FAO/WHO. (1961) Evaluation of the carcinogenic hazards of food
    additives. Fifth report of the Joint FAO/WHO Expert Committee on Food
    Additives. FAO Nutrition Meetings Report Series, No. 29; Wld Hlth
    Org. techn. Rep. Ser., No. 220.

    FAO/WHO. (1964) Evaluation of the toxicity of pesticide residues in
    food, report of a Joint Meeting of the FAO Committee on Pesticides in
    Agriculture and the WHO Expert Committee on Pesticide Residues. FAO
    Meeting Report, No. PL/1963/13; WHO/Food Add./23(1964).

    FAO/WHO. (1965a) Evaluation of the toxicity of pesticide residues in
    food; report of the Second Joint Meeting of the FAO Committee on
    Pesticides in Agriculture and the WHO Expert Committee on Pesticide
    Residues. FAO Meeting Report, No. PL:1965/10; WHO/Food Add./26.65.

    FAO/WHO. (1965b) Evaluation of the toxicity of pesticide residues in
    food. FAO Meeting Report, No. PL:1965/10/1; WHO/Food Add./27.65.

    FAO/WHO. (1965c) Evaluation of the hazards to consumers resulting from
    the use of fumigants in the protection of food. FAO Meeting Report,
    No. PL:1965/10/2; WHO/Food. Add./28.65.

    FAO/WHO. (1967a) Pesticide residues in food. Joint report of the FAO
    Working Party on Pesticide Residues and the WHO Expert Committee on
    Pesticide Residues. FAO Agricultural Studies, No. 73; Wld Hlth
    Org. techn. Rep. Ser., No. 370.

    FAO/WHO. (1967b) Evaluation of some pesticide residues in food.
    FAO:PL/CP/15; WHO/Food Add./67.32.

    FAO/WHO. (1968a) Pesticide residues. Report of the 1967 Joint Meeting
    of the FAO Working Party and the WHO Expert Committee. FAO Meeting
    Report, No. PL: 1967/M/11; Wld Hlth Org. techn. Rep. Ser., No.
    391.

    FAO/WHO. (1968b) 1967 evaluation of some pesticide residues in food.
    FAO/PL:1967/M/11/1; WHO/Food Add./68.30.

    FAO/WHO. (1969a) Pesticide residues in food. Report of the 1968 Joint
    Meeting of the FAO Working Party of Experts on Pesticide Residues and
    the WHO Expert Committee on Pesticide Residues. FAO Agricultural
    Studies, No. 78; Wld Hlth Org. techn. Rep. Ser., No. 417.

    FAO/WHO. (1969b) 1969 evaluations of some pesticide residues in food.
    FAO/PL:1968/M/9/1; WHO/Food Add./69.35.

    FAO/WHO. (1970a) Pesticide residues in food. Report of the 1969 Joint
    Meeting of the FAO Working Party of Experts on Pesticide Residues and
    the WHO Expert Group on Pesticide Residues. FAO Agricultural Studies,
    No. 84; Wld Hlth Org. techn. Rep. Ser., No. 458.

    FAO/WHO. (1970b) 1969 evaluations of some pesticide residues in food.
    FAO/PL:1969/M/17/1; WHO/Food Add./70.38.

    FAO/WHO. (1971a) Pesticide residues in food. Report of the 1970 Joint
    Meeting of the FAO Working Party of Experts on Pesticide Residues and
    the WHO Expert Group on Pesticide Residues. FAO Agricultural
    Studies, No. 87; Wld Hlth. Org. techn. Rep. Ser., No. 474.

    FAO/WHO. (1971b) 1970 evaluations of some pesticide residues in food.
    AGP:1970/M/12/1; WHO/Food Add./71.42.

    FAO/WHO. (1972a) Pesticide residues in food. Report of the 1971 Joint
    Meeting of the FAO Working Party of Experts on Pesticide Residues and
    the WHO Expert Committee on Pesticide Residues. FAO Agricultural
    Studies, No. 88; Wld Hlth Org. techn. Rep. Ser., No. 502.

    FAO/WHO. (1972b) 1971 evaluations of some pesticide residues in food.
    AGP-1971/M/9/1; WHO Pesticide Residues Series, No. 1.

    FAO/WHO. (1973a) Pesticide residues in food. Report of the 1972 Joint
    Meeting of the FAO Working Party of Experts on Pesticide Residues and
    of the WHO Expert Committee on Pesticide Residues. FAO Agricultural
    Studies, No. 90; Wld Hlth Org. techn. Rep. Ser., No. 525.

    FAO/WHO. (1973b) 1972 evaluations of some pesticide residues in food.
    AGP:1972/M/9/1; WHO Pesticide Residues Series, No. 2.

    FAO/WHO. (1974a) Pesticide residues in food. Report of the 1973 Joint
    Meeting of the FAO Working Party of Experts on Pesticide Residues and
    the WHO Expert Committee on Pesticide Residues. FAO Agricultural
    Studies, No. 92; Wld Hlth Org. techn. Rep. Ser., NO. 545.

    FAO/WHO. (1974b) 1973 Evaluations of some pesticide residues in food.
    AGP/1973/M/9/1; WHO Pesticide Residues Series, No. 3.

    FAO/WHO. (1975a) Pesticide residues in food. Report of the 1974 Joint
    Meeting of the FAO Working Party of Experts on Pesticide Residues and
    of the WHO Expert Committee on Pesticide Residues. FAO Agricultural
    Studies, No. 97; Wld Hlth Org. techn. Rep. Ser., No. 574.

    FAO/WHO. (1975b) 1974 evaluations of some pesticide residues in food.
    AGP/1974/M/11; WHO Pesticide Residue Series, No. 4.

    WHO. (1967) Procedures for investigating intentional and unintentional
    food additives. Report of a WHO Scientific Group. Wld Hlth Org.
    techn. Rep. Ser., No. 348.

    WHO. (1971) Evaluation and testing of drugs for mutagenicity:
    principles and problems. Report of a WHO Scientific Group. Wld Hlth
    Org. techn. Rep. Ser., No. 482.

    WHO. (1974) Assessment of mutagenicity and carcinogenicity of
    chemicals. Report of a WHO Scientific Group. Wld Hlth Org. techn.
    Rep. Ser., No. 546.
    





















    See Also:
       Toxicological Abbreviations