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    RECOMMENDATIONS CONCERNING ACCEPTABLE DAILY INTAKES AND RESIDUE
    LIMITS MADE AT THE 1973 MEETING

         These recommendations are additional to, or amend, those recorded
    in Annex 1 of the Report of the 1972 Meeting (FAO/WHO, 1973a) entitled
    "Index to Documentation and Summary of Recommendations Concerning
    Acceptable Daily Intakes, Tolerances, Practical Residue Limits, and
    Guideline Levels as of November 1972".

         Temporary recommendations are denoted by superscripts a,b,c,d, or e
    indicating that further work is to be made available not later than 30
    June in the year 1974, 1975, 1976 or 1977 respectively.

         Further exploratory notes are given at the end of this table.

        ANNEX I

                                                                                                                                              
                     Maximum                                                       Residue limits
                     acceptable                                                        (mg/kg)
    Pesticides       daily                                                                          
    and              intake        Commodity                                   Tolerances                  Remarks
    references1      (mg/kg                                                    (practical
                     bw)                                                       limits         Guideline
                                                                               indicated      levels2
                                                                               as (P))
                                                                                                                                              

    Azinphos-ethyl                 Tomatoes                                                   1            Residues to be determined as
                                   Apples, pears                                              0.5          azinphos-ethyl and its P = O
                                   Vegetables (except potatoes and                                         analogue and expressed as 
                                   tomatoes)                                                  0.5          azinphos-ethyl
                                   Soybeans, (dry)                                            0.2
                                   Potatoes, cotton-seed, rape seed                           0.05*

    Azinphos-methyl  0.0025        Almond hulls                                10                          Where azinphos-ethyl also occurs the
                                   Peaches                                     4                           total residue should not exceed the
    1969b, 1973b                   Citrus fruit                                2                           levels recommended for 
                                   Melons                                      2                           azinphos-methyl except in the case
                                   Celery                                      2                           of tomatoes, when the total should not
                                   Alfalfa (green), pea vines, soybean                                     exceed 1 mg/kg.
                                   vines                                       2                           Tolerances no longer temporary
                                   Fruit (except Apricots, citrus fruit,
                                   grapes, melons, peaches)                    1
                                   Broccoli, Brussels sprouts                  1
                                   Vegetables (except broccoli, Brussels
                                   sprouts, celery)                            0.5
                                   Potatoes                                    0.2
                                   Almonds (shelled but.)                      0.2
                                   Raw cereals, dry soybeans, cotton
                                   seed, sunflower seed                        0.2

    Benomyl                        Bean vines                                                 30           Residues to be determined as the
                                   Cherries, citrus fruit, grapes,                                         sum of benomyl and carbendazim
                                   peaches                                                    10           (MBC) and calculated as MBC

                                                                                                                                              
                     Maximum                                                       Residue limits
                     acceptable                                                        (mg/kg)
    Pesticides       daily                                                                         
    and              intake        Commodity                                   Tolerances                  Remarks
    references1      (mg/kg                                                    (practical
                     bw)                                                       limits         Guideline
                                                                               indicated      levels2
                                                                               as (P))
                                                                                                                                              

                                   Apples, apricots, pears, black
                                   berries, blackcurrants, boysenberries,
                                   dewberries, loganberries,
                                   raspberries, strawberries,
                                   tomatoes, sugarbeet tops                                   5
                                   Nectarines, plums, prunes, beans
                                   (lima, snap), beans (dry), celery,
                                   mangoes, barley straw, peanut hay                          2
                                   Bananas, mushrooms, almond hulls                           1
                                   Avocados, Brussels sprouts
                                   cucumbers, melons, squash                                  0.5
                                   Raw cereals, potatoes, sugar beets,
                                   almonds, macadamia nuts, peanuts,
                                   pecans                                                     0.1*
                                   Meat of cattle and sheep, whole milk                       0.1*

    Bromo-propylate  0.008         Apples, bananas, cherries, citrus
                                   fruit, grapes, nectarines,
                                   peaches, pears, plums, prunes,
                                   strawberries, hops (dried), tea
                                   (manufactured)                              5
                                   Vegetables, cotton-seed                     1
                                   Bananas (pulp), citrus fruit (pulp)         0.2

    Camphechlor                    Fat of meat of cattle, goat, pigs                                       Listed as toxaphene in FAO/WHO
    1969b                          and sheep                                                  5            1969b
                                   Beans (snap, dry, lima), broccoli,
                                   Brussels sprouts, cabbage, carrots,
                                   cauliflower, celery, collards,
                                   eggplant, kale, kohirabi,

                                                                                                                                              
                     Maximum                                                       Residue limits
                     acceptable                                                        (mg/kg)
    Pesticides       daily                                                                          
    and              intake        Commodity                                   Tolerances                  Remarks
    references1      (mg/kg                                                    (practical
                     bw)                                                       limits         Guideline
                                                                               indicated      levels2
                                                                               as (P))
                                                                                                                                              

                                   lettuce, okra, onions, parsnips,
                                   peas, peppers, pimentoes, pineapples,
                                   radishes, rutabegas, spinach,
                                   tomatoes, bananas (whole),
                                   nuts (shelled)                                             2
                                   Raw cereals (barley, oat, rice,
                                   in husk), rye, sorghum, wheat                              2
                                   Maize (grain), peanut (groundnut),
                                   rice (polished), soybeans (dry)                            0.5
                                   Cotton-seed oil, peanut oil (refined),
                                   rapeseed oil (refined), soybean oil
                                   (refined)                                                  0.5
                                   Milk and milk products (fat basis)                         0.5

    Captafol         0.05d         Cranberries, leeks                          8d                          Recommendations relate only to the
    1970b                          Apples, pears, eggplants                    5d                          parent compound. Referred to as
                                   Pumpkins                                    2d                          Difolotan in FAO/WHO 1969a, p. 18
                                   Carrots, onions (bulb), potatoes            0.5d
                                   Macadmia nuts (shelled)                     0.1d
    Captan           0.1           Apples, cherries                            40
    1970b, 1974                    Pears                                       30
                                   Apricots, blueberries, blackcurrants,
                                   redcurrants, strawberries                   20
                                   Spinach                                     20
                                   Citrus fruit, peaches, plums                15
                                   Endive, rhubarb, tomatoes                   15
                                   Cransberries, raspberries                   10
                                   Green beans, cucumbers, lettuce,
                                   peppers                                     10
                                   Raisins                                     5

                                                                                                                                              
                     Maximum                                                       Residue limits
                     acceptable                                                        (mg/kg)
    Pesticides       daily                                                                          
    and              intake        Commodity                                   Tolerances                  Remarks
    references1      (mg/kg                                                    (practical
                     bw)                                                       limits         Guideline
                                                                               indicated      levels2
                                                                               as (P))
                                                                                                                                              

    Carbaryl         0.01          Animal feedstuffs (green), alfalfa,
    1967b, 1968b,                  bean and pea vines, clover corn
    1969b, 1970b,                  forage, cowpea foliage, grasses,
    1971b                          peanut hay, sorghum forage, soybean
                                   foliage, sugar beet tops                    100
                                   Cherries, plums, sorghum grain              10
                                   Cranberries                                 7
                                   Pears                                       5
                                   Rice (rough)                                3
                                   Root crops (beats, carrots,
                                   parsnips, radishes, rutabagas),
                                   peanuts (whole)                             2
                                   Cowpeas, soybeans (dry)                     1
                                   Egg (shell-free)                            0.5
                                   Sugarbeets, meat of cattle, goats
                                   and sheep                                   0.2

    Carbendazim                    Cherries, citrus fruit, grapes,
    1974b                          peaches                                                    10
                                   Apples, pears, gooseberries, straw
                                   berries, lettuce, tomatoes, sugar
                                   beet tops                                                  5
                                   Plums, beans (dwarf), celery,
                                   gherkins                                                   2
                                   Bananas (whole), mushrooms                                 1
                                   Cucumbers, melons, bananas (pulp)                          0.5
                                   Raw cereals, sugar beet, coffee
                                   beans (raw)                                                0.1*

                                                                                                                                              
                       Maximum                                                     Residue limits
                       acceptable                                                      (mg/kg)
    Pesticides         daily                                                                        
    and                intake      Commodity                                   Tolerances                  Remarks
    references1        (mg/kg                                                  (practical
                       bw)                                                     limits         Guideline
                                                                               indicated      levels2
                                                                               as (P))
                                                                                                                                              

    Demeton-S-ethyl,   0.005       Currants (black and red), grapes            2                           The ADI refers to the sum of the
                                   Apples, peaches, plums                      1                           compounds, demetm-S-methyl, oxy
    oxydemeton-methyl,             Citrus fruit pears, blackberries,                                       demeton-methyl, and demeton-A
    and                            gooseberries, raspberries,                                              methyl sulfone.
    demeton-S-ethyl                strawberries, lettuce, summer squash        0.5                         The tolerances are to apply to the
    sulfone                        Raw cereals                                 0.2                         sum of the three compounds
                                   Pears, peas, broccoli, Brussels                                         determined as the sulfers, and
                                   sprouts, cabbage, cauliflower,                                          calculated as demeton-S-ethyl
                                   cantaloupes, cucumbers, eggplant,
                                   pumpkins, watermelons, winter
                                   squash, potatoes                            0.2
                                   Cotton-seed, sugar beet, turnips            0.1
                                   Meat and fat of cattle, pigs, sheep
                                   and poultry; milk and milk products;
                                   eggs (shell-free)                           0.05*
                                   Nuts (shelled)                              0.05*
                                   Animal feed (green)                         5
                                   Animal feed (dry)                           10

    Dimethoate                     Strawberries                                0.3                         From use of formotion and/or
    1971b                          Blackcurrants                               2.0                         dimethoate

    Disufoton          0.001c      Vegetables, including beans,                                            Residue to be determined as
                                   broccoli, Brussels sprouts                                              disulfoton sulfone and 
                                   cabbage, cauliflower, lettuce,                                          demeton-S-sulfone and expressed as 
                                   rice (in husk), sugar beet                  0.5c                        disulfoton
                                   Cereals (except rice); cotton-seed          0.2c
                                   Coffee beans, peanut (kernels),
                                   pecans (dry), pineapple                     0.1*c
                                   Forage crops (green)                        5c

                                                                                                                                              
                       Maximum                                                       Residue limits
                       acceptable                                                        (mg/kg)
    Pesticides         daily                                                                          
    and                intake          Commodity                                 Tolerances                Remarks
    references1        (mg/kg                                                    (practical
                       bw)                                                       limits       Guideline
                                                                                 indicated    levels2
                                                                                 as (P))
                                                                                                                                              

    Folpet             0.1         Strawberries                                  20                        Recommendations apply only to parent
    1970b                          Lettuce                                       15                        compound. Previous recommendations
                                                                                                           except for strawberries are 
                                                                                                           confirmed and are no longer
                                                                                                           temporary

    Formothion         0.02        Citrus fruit                                  0.2                       The tolerance refers only to the
    1970b, 1973b                                                                                           parent compound. The metabolites
                                                                                                           dimethoate and omethoate arising
                                                                                                           from the use of formothion are
                                                                                                           included in the tolerances
                                                                                                           established for these compounds

    Hexachloro-benzene See         Milk and milk products (fat basis)          0.5 (P)                     Intake of 0.0006 g/kg daily is
                       remarks     Raw cereals                                 0.05 (P)                    considerably below any dosage rate
    1970b                          Flour and similar milled cereal                                         known to be harmful (see section
                                   products                                    0.01 (P)                    Other residue limits recommended
                                                                                                           in 1969 confirmed

    Lindane            0.01e       Fat of meat of cattle, pigs and                                        Referred to as gamma-BHE prior to
    1967b, 1969b                   sheep                                       2e                         1967. In FAO/WHO 1973a, for fat
    1972b                          Apples, Pears                               1e                         meat etc. 2 mg/kg was
                                   Rice (in husk)                              0.5e                       erroneously listed as a practical
                                   Milk and milk products (fat basis)          0.1 (p)e                   residue limit instead of as
                                   Sugar beet (roots), sugar beat (tops)       0.2e                       tolerance
                                   Eggs (shell-free)                           0.1 (p)e

    Malathion          0.02        Pulses (dried beans, lentils)               8
    1967b, 1968b,
    1969b, 1971b

                                                                                                                                              
                       Maximum                                                     Residue limits
                       acceptable                                                      (mg/kg)
    Pesticides         daily                                                                        
    and                intake      Commodity                                   Tolerances                  Remarks
    references1        (mg/kg                                                  (practical
                       bw)                                                     limits         Guideline
                                                                               indicated      levels2
                                                                               as (P))
                                                                                                                                              

    Propoxur            0.02       Animal feedstuffs (green)                   5                           Recommendations include main
                                   Apples, cherries, peaches, pears,                                       metabolites expressed as propoxur
                                   plums                                       3
                                   Blackberries, gooseberries, 
                                   red-currants, strawberries                  3
                                   Vegetables (except potatoes and
                                   root vegetables)                            3
                                   Potatoes, root vegetables                   0.5
                                   Rice grain (rough)                          0.5
                                   Rice (hulled)                               0.1
                                   Cocoa beans                                 0.05*
                                   Meat                                        0.05*
                                   Milk (whole)                                0.05*

    Quintozene          0.001c     Lettuce                                     3c
    1970b                          Peanuts (kernels)                           2c

    Thiometon           0.005d     Apples, cherries (sweet), grapes,                                       Residues are to be determined as
    1970b                          pears, peaches, plum, strawberries,                                     thiometon-sulfone and expressed
                                   beans, lettuce, peas,                                                   as thiometon
                                   peppers, tomatoes, hops (dry)               0.5d
                                   Carrots, potatoes, sugarbeet, raw
                                   cereals, including maize                    0.05*

    Thiophanate-methyl  0.08       Celery                                      20b                         Residues to be determined as
                                   Cherries, citrus fruit, grapes,                                         thiophanate-methyl and carbendazim
                                   peaches, raspberries                        10b                         (MBC) and expressed as carbendazim
                                   Apples, pears, blackcurrants,
                                   gooseberries, strawberries,
                                   carrots, lettuce, tomatoes,
                                   sugarbeet (tops)                            5b

                                                                                                                                              
                       Maximum                                                     Residue limits
                       acceptable                                                      (mg/kg)
    Pesticides         daily                                                                        
    and                intake      Commodity                                   Tolerances                  Remarks
    references1        (mg/kg                                                  (practical
                       bw)                                                     limits         Guideline
                                                                               indicated      levels2
                                                                               as (P))
                                                                                                                                              

    Thiophanate-methyl             Plums, beans, (broad, dwarf, French
                                   runner, kidney), gherkins                   2b
                                   Bananas (whole), mushrooms                  1b
                                   Cucumber                                    0.5b
                                   Raw cereals, onions, sugarbeets             0.1*b

    Tricyclohe-xyltin  0.007e      Citrus fruit, tea (manufactured)            2e                          Expressed as the patent compound
    hydroxide                      Meat                                        0.2 (P)e
    1971b                          Milk and milk products (fat basis)          0.5 (P)e
    

    Vemidothion                    Apples, pears                                              2
    1974                           Brussels sprouts                                           1
                                   Grapes, sugarbeets                                         0.5
                                                                                                                                              

    1    References are to FAO/WHO publications (see list of references on p. 26). Date sof publications refer to the 
         first complete or completely revised monograph or to important mentions of the compound in a report. Where a
         monograph has been completely revised mention is not necessarily made of any earlier ones. Where no date is given,
         the compound as considered at the 1973 Joint Meeting for the first time.

    2    Guideline levels are included to assist administering authorities, even though ADIs have not been established
         for the individual products, or temporary ADIs established at an earlier date have been withdrawn.  The levels
         recommended are those that need not be exceeded if good practices are followed.

    *    Level at or about the limit of determination.

    


    ANNEX II

    REFERENCES

    FAO/WHO (1958) Procedures for the testing of intentional food
    additives to establish their safety for use. Second report of the
    Joint FAO/WHO Expert Committee on Food Additives. FAO Nutrition
    Meetings Report Series, No. 17; Wld Hlth Org. techn. Rep. Ser., No.
    144

    FAO/WHO (1961) Evaluation of the carcinogenic hazards of food
    additives. Fifth report of the Joint FAO/WHO Expert Committee on Food
    Additives. FAO Nutrition Meetings Report Series, No. 29; Wld Hlth
    Org. techn. Rep. Ser., No. 220

    FAO/WHO (1964) Evaluation of the toxicity of pesticide residues in
    food; report of a Joint Meeting of the FAO Committee on Pesticides in
    Agriculture and the WHO Expert Committee on Pesticide Residues. FAO
    Meeting Report, No. PL/1963/13; WHO/Food Add/23(1964)

    FAO/WHO (1965a) Evaluation of the toxicity of pesticide residues in
    food; report of the Second Joint Meeting of the FAO Committee on
    Pesticides in Agriculture and the WHO Expert Committee on Pesticide
    Residues. FAO Meeting Report, No. PL:1965/10; WHO/Food Add/26.65

    FAO/WHO (1965b) Evaluation of the toxicity of pesticide residues in
    food. FAO Meeting Report, No. PL:1965/10/1; WHO/Food Add/27.65

    FAO/WHO (1965c) Evaluation of the hazards to consumers resulting from
    the use of fumigants in the protection of food. FAO Meeting Report,
    No. PL:1965/10/2; WHO/Food Add/28.65

    FAO/WHO (1967a) Pesticide residues in food. Joint report of the FAO
    Working Party on Pesticide, Residues and the WHO Expert Committee on
    Pesticide Residues. FAO Agricultural Studies, No. 73; Wld Hlth Org.
    techn. Rep. Ser., No. 370

    FAO/WHO (1967b) Evaluation of some pesticide residues in food.
    FAO:PL/CP/15; WHO/Food Add/67.32

    FAO/WHO (1968a) Pesticide residues. Report of the 1967 Joint Meeting
    of the FAO Working Party and the WHO Expert Committee. FAO Meeting
    Report, No. PL:1967/M/11; Wld Hlth Org. techn. Rep. Ser., No. 391

    FAO/WHO (1968b) 1967 evaluation of some pesticide residues in food.
    FAO/PL:1967/M/11/1; WHO/Food Add/68.30

    FAO/WHO (1969a) Pesticide residues in food. Report of the 1968, Joint
    Meeting of the FAO Working Party of Experts on Pesticide Residues and
    the WHO Expert Committee on Pesticide Residues. FAO Agricultural
    Studies, No. 78; Wld Hlth Org. techn. Rep. Ser., No. 417

    FAO/WHO (1969b) 1969 evaluations of some pesticide residues in food.
    FAO/PL:1968/M/9/1; WHO/Food Add./69.35

    FAO/WHO (1970a) Pesticide residues in food. Report of the 1969 Joint
    Meeting of the FAO Working Party of Experts on Pesticide Residues and
    the WHO Expert Group on Pesticide Residues. FAO Agricultural
    Studies, No. 84; Wld Hlth Org. techn. Rep. Ser., No. 458

    FAO/WHO (1970b) 1969 evaluations of some pesticide residues in food.
    FAO/PL:1969/M/17/1; WHO/Food Add./70.38

    FAO/WHO (1971a) Pesticide residues in food. Report of the 1970 Joint
    Meeting of the FAO Working Party of Experts on Pesticide Residues and
    the WHO Expert Group on Pesticide Residues. FAO Agricultural
    Studies, No. 87; Wld Hlth Org. techn. Rep. Ser., No. 474

    FAO/WHO (1971b) 1970 evaluations of some pesticide residues in food.
    AGP:1970/M/12/1; WHO/Food Add./71.42

    FAO/WHO (1972a) Pesticide residues in food. Report of the 1971 Joint
    Meeting of the FAO Working Party of Experts on Pesticide Residues and
    the WHO Expert Committee on Pesticide Residues. FAO Agricultural
    Studies, No. 88; Wld Hlth Org. techn. Rep. Ser., No. 502

    FAO/WHO (1972b) 1971 evaluations of some pesticide residues in food.
    AGP-1971/M/9/1; WHO Pesticide Residues Series, No. 1

    FAO/WHO (1973a) Pesticide residues in food. Report of the 1972 Joint
    Meeting of the FAO Working Party of Experts on Pesticide Residues and
    of the WHO Expert Committee on Pesticide Residues. FAO Agricultural
    Studies, No. 90; Wld Hlth Org. techn. Rep. Ser., No. 525

    FAO/WHO (1973b) 1972 evaluations of some pesticide residues in food.
    AGP:1972/M/9/1; WHO Pesticide Residues Series, No. 2

    FAO/WHO (1974a) Pesticide residues in food. Report of the 1973 Joint
    Meeting of the FAO Working Party on Pesticide Residues and the WHO
    Expert Committee on Pesticide Residues. FAO Agricultural Studies No.
    92; Wld Hlth Org. techn. Rep. Ser., No. 545

    WHO (1967) Procedures for investigating intentional and unintentional
    food additives. Report of a WHO Scientific Group. Wld Hlth Org.
    techn. Rep. Ser., No. 348

    WHO (1971) Evaluation and testing of drugs for mutagenicity:
    principles and problems. Report of a WHO Scientific Group. Wld Hlth
    Org. techn. Rep. Ser., No. 482

    WHO (1974) Assessment of mutagenicity and carcinogenicity of
    chemicals. Report of a WHO Scientific Group. Wld Hlth Org. techn.
    Rep. Ser., No. 546
    





















    See Also:
       Toxicological Abbreviations