IPCS INCHEM Home

Summary of Evaluations Performed by the
Joint FAO/WHO Expert Committee on Food Additives

FLUMEQUINE
Chemical names: 9-FLUORO-6,7-DIHYDRO-5-METHYL-1-OXO-1H,5H-BENZO[ij]-QUINOLIZINE-2-CARBOXYLIC ACID
Synonyms: R-802; APURONE
Functional class: VETERINARY DRUG (ANTIMICROBIAL AGENT)
Latest evaluation: 2004
ADI: 0-0.03 mg/kg bw
Comments/MRLs: MRLs (expressed as flumequine): Muscle and liver (cattle, chickens, pigs, and sheep): 0.5 mg/kg; muscle (black tiger shrimp (P. monodon)): 0.5 mg/kg (temporary); muscle including normal proportions of skin (trout): 0.5 mg/kg; kidney (cattle, chickens, pigs, and sheep): 3 mg/kg; fat (cattle, chickens, pigs, and sheep): 1 mg/kg
Report: TRS 925-JECFA 62/18
Residues: FNP 41/15-JECFA 60/43 (2003)
Tox monograph: FAS 53-JECFA 62/93
Previous status: 2003, TRS 918-JECFA 60/11, FNP 41/15-JECFA 60/43, FAS 51-JECFA 60/25. ADI WITHDRAWN. ALL THE MRLS IN CATTLE, PIGS, SHEEP, CHICKENS, AND TROUT THAT HAD BEEN RECOMMENDED AT PREVIOUS MEETINGS WERE WITHDRAWN BECAUSE THE ADI WAS WITHDRAWN. NO. O
2000, TRS 900-JECFA 54/9, FNP 41/13-JECFA 54/43, FAS39-JECFA 48/63 (1997). 0-0.03 mg/kg (1997). MRLs (in mg/kg): MUSCLE AND LIVER (CATTLE, PIGS, SHEEP, AND CHICKENS): 0.5; TROUT MUSCLE/SKIN IN NORMAL PROPORTIONS: 0.5; KIDNEY (CATTLE, PIGS, SHEEP, AND CHICKENS): 3; FAT (CATTLE, PIGS, SHEEP, AND CHICKENS): 1. FU, MRL
1997, TRS 879-JECFA 48/35, FNP 41/10-JECFA 48/59, FAS 39-JECFA 48/63. 0-0.03 mg/kg. MRLs (in mg/kg): MUSCLE (CATTLE): 0.5; LIVER AND FAT (CATTLE): 1; KIDNEY (CATTLE): 3; MRLs (TEMPORARY): MUSCLE (PIGS, SHEEP AND CHICKENS): 0.5; MUSCLE/SKIN IN NORMAL PROPORTIONS (TROUT): 0.5; LIVER AND FAT (PIGS, SHEEP AND CHICKENS): 1; KIDNEY (PIGS, SHEEP AND CHICKKENS): 3. FU. MRL/TMRL
1994, TRS 851-JECFA 42/15, NOT PREPARED, FAS 33-JECFA 42/35, NO ADI ALLOCATED, NO, O
 
28 Jan 06    




    See Also:
       Toxicological Abbreviations
       Flumequine (JECFA Food Additives Series 51)
       Flumequine (WHO Food Additives Series 53)
       Flumequine (WHO Food Additives Series 33)
       Flumequine (WHO Food Additives Series 39)