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Summary of Evaluations Performed by the
Joint FAO/WHO Expert Committee on Food Additives

CYHALOTHRIN
Chemical names: (RS)-alpha-CYANO-3-PHENOXYBENZYL (Z)-(1RS,3RS)-2-(CHLORO-3,3,3-TRIFLUOROPROPENYL)-2,2-DIMETHYLCYCLOPROPANECARBOXYLATE
Synonyms: PT-563; COOPERTRIX?; GRENADEĀ®
Functional class: VETERINARY DRUG (INSECTICIDE)
Latest evaluation: 2004
ADI: 0-0.005 mg/kg bw
Comments/MRLs: MRLs (expressed as cyhalothrin): Muscle and kidney (cattle, pigs, and sheep): 0.02 mg/kg; liver (cattle and pigs): 0.02 mg/kg; liver (sheep): 0.05 mg/kg; fat (cattle, pigs, and sheep): 0.4 mg/kg; milk (cattle): 0.03 mg/kg
Report: TRS 925-JECFA 62/10,70
Residues: FNP 41/13-JECFA 54/1 (2000)
Tox monograph: FAS 53-JECFA 62/85
Previous status: 2002, TRS 911-JECFA 58/36, FNP 41/13-JECFA 54/1 (2000), FAS 45-JECFA 54/41 (2000). 0-0.002 mg/kg bw (TEMPORARY). THE COMMITTEE EXTENDED THE TEMPORARY ADI THAT WAS ESTABLISHED AT THE FIFTY-FOURTH MEETING (2000), PENDING THE RESULTS OF STUDIES APPROPRIATE FOR IDENTIFYING A NOEL FOR NEUROBEHAVIOURAL EFFECTS IN LABORATORY ANIMALS. THE RESULTS OF THESE STUDIES ARE REQUIRED FOR EVALUATION IN 2004. THE COMMITTEE EXTENDED THE TEMPORARY MRL OF 0.02 MG/KG FOR SHEEP LIVER THAT WAS ESTABLISHED AT THE FIFTY-FOURTH MEETING (2000), AND REQUIRED ADDITIONAL ANALYTICAL DATA FOR EVALUATION IN 2004. THE TEMPORARY MRLS FOR OTHER TISSUES RECOMMENDED AT THE FIFTY-FOURTH MEETING WERE ALSO EXTENDED, PENDING RECONSIDERATION OF THE TEMPORARY ADI IN 2004. TE. TMRL.
2000, TRS 900-JECFA 54/30, FNP 41/13-JECFA 54/1, FAS 45-JECFA 54/41. 0-0.002 mg/kg bw (TEMPORARY, 2000) PENDING NEUROBEHAVIOURAL NOEL DUE BY 2002; MRLs (TEMPORARY, EXPRESSED AS THE SUM OF CONCENTRATIONS OF THE ISOMERS OF CYHALOTHRIN): MUSCLE, LIVER AND KIDNEY (CATTLE, PIGS AND SHEEP): 0.02 mg/kg; FAT (CATTLE, PIGS AND SHEEP): 0.4 mg/kg; MILK (CATTLE): 0.03 mg/l. TE. TMRL
 
28 Jan 06    




    See Also:
       Toxicological Abbreviations
       Cyhalothrin (EHC 99, 1990)
       Cyhalothrin (ICSC)
       Cyhalothrin (WHO Food Additives Series 53)
       Cyhalothrin (WHO Food Additives Series 45)
       Cyhalothrin (Pesticide residues in food: 1984 evaluations)
       Cyhalothrin (Pesticide residues in food: 1984 evaluations)
       Cyhalothrin (UKPID)