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MECARBAM
ICSC: 1755
Peer-Review Status: 12.11.2010 Validated
S-(N-ethoxycarbonyl-N-methylcarbamoylmethyl) O,O-diethyl phosphorodithioate
Ethyl N-(diethoxythiophosphorylthio)acetyl-N-methylcarbamate
Ethyl 6-ethoxy-2-methyl-3-oxo-7-oxa-5-thia-2-aza-6-phosphanonanoate 6-sulfide 
CAS #: 2595-54-2 RTECS #: FB385000
UN #: 3018
EC #: 015-045-00-1
EINECS #: 219-993-9
    Formula: C10H20NO5PS2
Molecular mass: 329.4

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames.  Use water spray, foam, powder, carbon dioxide. 
EXPLOSION      
 
EXPOSURE   PREVENT GENERATION OF MISTS!   
Inhalation Dizziness. Nausea. Muscle twitching. Sweating. Pupillary constriction. Muscle cramps. Excessive salivation. Vomiting. Diarrhoea. Laboured breathing. Convulsions. Cough. Blurred vision. Unconciousness.  Use ventilation, local exhaust or breathing protection.  Refer immediately for medical attention. 
Skin See Inhalation.  Protective gloves.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer immediately for medical attention. 
Eyes   Wear safety spectacles or eye protection in combination with breathing protection.  Rinse with plenty of water (remove contact lenses if easily possible). 
Ingestion See Inhalation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Refer immediately for medical attention. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: self-contained breathing apparatus. Do NOT let this chemical enter the environment. Absorb liquid in sand or inert absorbent. Carefully collect remainder. Store and dispose of according to local regulations.  Do not transport with food and feedstuffs. 
EC Classification
Symbol: T, N; R: 24/25-50/53; S: (1/2)-36/37-45-60-61 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: II 
GHS Classification
Signal: Danger
Fatal if swallowed
Toxic in contact with skin or if inhaled
Very toxic to aquatic life 
skull;toxicenviro;aqua

EMERGENCY RESPONSE SAFE STORAGE
  Provision to contain effluent from fire extinguishing. Separated from strong bases, strong oxidants and food and feedstuffs. Well closed. Store in an area without drain or sewer access. 

IMPORTANT DATA
Physical State; Appearance
OILY COLOURLESS LIQUID. 

Physical dangers
 

Chemical dangers
Decomposes on burning. This produces toxic and corrosive fumes including phosphorus oxides, nitrogen oxides and sulfur oxides. Reacts with strong bases and strong oxidants. 

Occupational exposure limits
TLV not established.
MAK (not established):. 

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. 

Inhalation risk
A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster. 

Effects of short-term exposure
Cholinesterase inhibition. The substance may cause effects on the nervous system. This may result in convulsions and respiratory depression. The effects may be delayed. Medical observation is indicated. Exposure could cause death. 

Effects of long-term or repeated exposure
Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point at 0.003kPa: 144°C
Melting point: 9°C
Density (at °C): 1.2 g/cm³
Solubility in water, g/100ml at 21°C: 0.1
Vapour pressure at 20°C: negligible
Relative vapour density (air = 1): 11.4
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.02
Octanol/water partition coefficient as log Pow: 2.29 (estimated) 
The substance is very toxic to aquatic organisms. This substance may be hazardous to the environment. Special attention should be given to bees. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal. 

NOTES
Depending on the degree of exposure, periodic medical examination is suggested.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
Carrier solvents used in commercial formulations may change physical and toxicological properties.
If the substance is formulated with solvents also consult the ICSCs of these materials. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations
       Mecarbam (Pesticide residues in food: 1980 evaluations)
       Mecarbam (Pesticide residues in food: 1983 evaluations)
       Mecarbam (Pesticide residues in food: 1986 evaluations Part II Toxicology)