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NICOTINAMIDE
ICSC: 1703
Peer-Review Status: 08.04.2008 Modified
Pyridine-3-carboxylamide
3-Pyridinecarboxamide
Niacinamide 
CAS #: 98-92-0 RTECS #: QS3675000
EINECS #: 202-713-4
    Formula: C6H6N2O
Molecular mass: 122.1

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.    Use water spray, foam, powder, carbon dioxide. 
EXPLOSION Finely dispersed particles form explosive mixtures in air.  Prevent deposition of dust. Closed system, dust explosion-proof electrical equipment and lighting.   
 
EXPOSURE   PREVENT DISPERSION OF DUST!   
Inhalation Cough.  Avoid inhalation of dust.  Fresh air, rest. 
Skin   Protective gloves.  Rinse skin with plenty of water or shower. 
Eyes Redness. Pain.  Wear safety goggles.  Rinse with plenty of water (remove contact lenses if easily possible). 
Ingestion   Do not eat, drink, or smoke during work.  Rinse mouth. Give one or two glasses of water to drink. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Wash away remainder with plenty of water.   
EC Classification
 
UN Classification
 
GHS Classification
Signal: Warning
Causes eye irritation 

EMERGENCY RESPONSE SAFE STORAGE
  Separated from oxidants. 

IMPORTANT DATA
Physical State; Appearance
WHITE CRYSTALLINE POWDER. 

Physical dangers
Dust explosion possible if in powder or granular form, mixed with air. 

Chemical dangers
On combustion, forms toxic gases including nitrogen oxides. Reacts with oxidants. 

Occupational exposure limits
TLV not established.
MAK (not established):. 

Routes of exposure
 

Inhalation risk
A nuisance-causing concentration of airborne particles can be reached quickly when dispersed, especially if powdered. 

Effects of short-term exposure
The substance is irritating to the eyes. 

Effects of long-term or repeated exposure
 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Sublimation
Melting point: 127-131°C
Density: 1.4 g/cm³
Solubility in water, g/100ml at 20°C: 100 (very good)
Vapour pressure, kPa at 35°C: 3.1
Relative vapour density (air = 1): 4.2
Flash point: 182°C
Auto-ignition temperature: 480°C
Octanol/water partition coefficient as log Pow: -0.38  
 

NOTES
 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations
       Nicotinamide (SIDS)