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1,2-DIMETHYLHYDRAZINE
ICSC: 1662
Peer-Review Status: 17.04.2007 Validated
Symmetrical dimethylhydrazine
N,N'-Dimethylhydrazine
SDMH 
CAS #: 540-73-8 RTECS #: MV2625000
UN #: 2382
EC #: 007-013-00-0
    Formula: C2H8N2 / H3CNHNHCH3
Molecular mass: 60.1

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Highly flammable. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames, NO sparks and NO smoking. NO contact with oxidizing agents.  Use water in large amounts, powder, alcohol-resistant foam, carbon dioxide. 
EXPLOSION Vapour/air mixtures are explosive. Risk of fire and explosion on contact with oxidizing agents.  Closed system, ventilation, explosion-proof electrical equipment and lighting. Do NOT use compressed air for filling, discharging, or handling.  In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE   AVOID ALL CONTACT!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Cough. Sore throat. See Notes.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Refer immediately for medical attention. 
Skin MAY BE ABSORBED! See Notes.  Protective gloves. Protective clothing.  First rinse with plenty of water for at least 15 minutes, then remove contaminated clothes and rinse again. Refer immediately for medical attention. 
Eyes Redness. Pain.  Wear face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion See Notes.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Refer immediately for medical attention. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT absorb in saw-dust or other combustible absorbents.  Do not transport with food and feedstuffs.
Note: E 
EC Classification
Symbol: T, N; R: 45-23/24/25-51/53; S: 53-45-61 
UN Classification
UN Hazard Class: 6.1; UN Subsidiary Risks: 3; UN Pack Group: I 
GHS Classification
Signal: Danger
Highly flammable liquid and vapour
Fatal if swallowed
Fatal in contact with skin
Fatal if inhaled
Causes eye irritation
Suspected of causing genetic defects
May cause cancer
Causes damage to liver and kidneys through prolonged or repeated exposure 
flam;flameskull;toxiccancer;health haz

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61GTF1-1.  Fireproof. Separated from strong oxidants. Well closed. Store in an area without drain or sewer access. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS FUMING HYGROSCOPIC LIQUID WITH PUNGENT ODOUR. TURNS YELLOW ON EXPOSURE TO AIR. 

Physical dangers
The vapour is heavier than air and may travel along the ground; distant ignition possible. 

Chemical dangers
Decomposes on burning. This produces toxic fumes including nitrogen oxides. The substance is a strong reducing agent. It reacts violently with oxidants. Reacts violently with acids. This generates fire and explosion hazard. Attacks plastic, rubber and coatings. 

Occupational exposure limits
TLV (NOT-ESTABLISHED):.
MAK: Carcinogen category: 2; Skin absorption (H); Sensitization of skin (SH); (DFG 2006). 

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion. 

Inhalation risk
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance is irritating to the eyes and respiratory tract. Exposure could cause death. 

Effects of long-term or repeated exposure
The substance may have effects on the kidneys and liver. This may result in tissue lesions. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 81°C
Melting point: -9°C
Density: 0.83 g/cm³
Solubility in water, g/100ml at 25°C: 100
Vapour pressure, kPa at 25°C: 9
Relative vapour density (air = 1): 2.07
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.1
Flash point: <5°C
Explosive limits, vol% in air: 2.4 - 20
Octanol/water partition coefficient as log Pow: -0.54 (estimated) 
This substance may be hazardous to the environment. Special attention should be given to fish. 

NOTES
Insufficient data are available on the effect of this substance on human health, therefore utmost care must be taken.
Rinse contaminated clothes with plenty of water because of fire hazard.
Environmental effects from the substance have not been investigated.
Data on similar substances suggest that there may be environmental effects of this substance. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations