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CYCLOHEXANEDICARBOXYLIC ACID ANHYDRIDE
ICSC: 1643
Peer-Review Status: 10.11.2006 Validated
1,3-Isobenzofurandione, hexahydro-
Cyclohexane-1,2-dicarboxylic acid anhydride
Hexahydro-isobenzofuran-1,3-dione
Hexahydrophthalic anhydride
HHPA 
CAS #: 85-42-7 EC #: 607-102-00-X
EINECS #: 201-604-9
    Formula: C8H10O3
Molecular mass: 154.2

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames.  Use water in large amounts. 
EXPLOSION      
 
EXPOSURE   AVOID ALL CONTACT!   
Inhalation Cough. Wheezing.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin Redness.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. 
Eyes Redness. Pain.  Wear face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Sore throat. Burning sensation. Abdominal pain. Diarrhoea.  Do not eat, drink, or smoke during work.  Rinse mouth. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers.   
EC Classification
Note: C; Symbol: Xn; R: 41-42/43; S: (2)-23-24-26-37/39 
UN Classification
 
GHS Classification
Signal: Danger
May cause allergic skin reaction
Causes serious eye irritation
Causes skin irritation
Harmful to aquatic life 
cancer;health haz

EMERGENCY RESPONSE SAFE STORAGE
  Dry. Store in an area without drain or sewer access. 

IMPORTANT DATA
Physical State; Appearance
SOLID IN VARIOUS FORMS. 

Physical dangers
 

Chemical dangers
Decomposes slowly on contact with water. This produces acid. 

Occupational exposure limits
TLV (inhalable vapor and aerosol): 0.005mg/m³ (ceiling value); (SEN); (ACGIH 2008).
MAK: Sensitization of respiratory tract (SA); (DFG 2008). 

Routes of exposure
The substance can be absorbed into the body by inhalation. 

Inhalation risk
 

Effects of short-term exposure
The substance is irritating to the skin. The substance is severely irritating to the eyes. 

Effects of long-term or repeated exposure
Repeated or prolonged contact may cause skin sensitization. Repeated or prolonged inhalation may cause asthma. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 296°C
Melting point: 35-36°C
Solubility in water: reaction
Vapour pressure, Pa at 25°C: 0.9
Relative vapour density (air = 1): 5.3
Octanol/water partition coefficient as log Pow: 21.4  
The substance is harmful to aquatic organisms. 

NOTES
The symptoms of asthma often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential.
Card has been partially updated in November 2008: see Occupational Exposure Limits, GHS classification. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations