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METHOXYFLURANE
ICSC: 1636
Peer-Review Status: 04.04.2006 ValidatedPeer-Review Status: GHS added Fast track Jan 08: GHS
2,2-Dichloro-1,1-difluoroethyl methyl ether
2,2-Dichloro-1,1-difluoro-1-methoxyethane
Methoflurane
Penthrane 
CAS #: 76-38-0 RTECS #: KN7820000
EINECS #: 200-956-0
    Formula: C3H4Cl2F2O / CH3OCF2CHCl2
Molecular mass: 165.0

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible.  NO open flames.  Use water spray, powder, foam, carbon dioxide. 
EXPLOSION Above 63°C explosive vapour/air mixtures may be formed.  Above 63°C use a closed system and ventilation.   
 
EXPOSURE      
Inhalation Dizziness. Drowsiness. Unconciousness.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. 
Skin   Protective gloves.  Rinse skin with plenty of water or shower. 
Eyes Redness.  Wear safety spectacles or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion   Do not eat, drink, or smoke during work.  Rinse mouth. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Collect leaking and spilled liquid in sealable metal containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.   
EC Classification
 
UN Classification
 
GHS Classification
Signal: Warning
Combustible liquid
May cause damage to kidneys if if inhaled 
cancer;health haz

EMERGENCY RESPONSE SAFE STORAGE
   

IMPORTANT DATA
Physical State; Appearance
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
 

Chemical dangers
Decomposes on burning. This produces toxic fumes of hydrogen chloride and hydrogen fluoride. Attacks some forms of plastic and rubber. 

Occupational exposure limits
TLV (NOT-ESTABLISHED):. 

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour. 

Inhalation risk
No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20°C. 

Effects of short-term exposure
Exposure at high levels could cause unconsciousness. 

Effects of long-term or repeated exposure
The substance may have effects on the kidneys. This may result in kidney impairment. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 105°C
Melting point: -35°C
Relative density (water = 1): 1.42
Solubility in water, g/100ml at 37°C: 2.83 (poor)
Vapour pressure, kPa at 20°C: 3.1
Relative vapour density (air = 1): 5.7
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.1
Flash point: 63°C
Explosive limits, vol% in air: 7-?
Octanol/water partition coefficient as log Pow: 2.21  
 

NOTES
 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations