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1-CHLORO-3-NITROBENZENE
ICSC: 1633
Peer-Review Status: 19.04.2007 Validated
Benzene, 1-chloro-3-nitro-
m-Chloronitrobenzene 
CAS #: 121-73-3 RTECS #: CZ0940000
UN #: 1578
EINECS #: 204-469-1
    Formula: ClC6H4NO2
Molecular mass: 157.6

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames.  Use water spray, foam, carbon dioxide. 
EXPLOSION Finely dispersed particles form explosive mixtures in air.     
 
EXPOSURE   PREVENT DISPERSION OF DUST! STRICT HYGIENE!   
Inhalation Blue lips, fingernails and skin. Dizziness. Headache. Nausea. Confusion. Convulsions.  Use local exhaust. Use breathing protection.  Fresh air, rest. Refer for medical attention. See Notes. 
Skin MAY BE ABSORBED! See Inhalation.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes Redness.  Wear safety goggles.  Rinse with plenty of water for several minutes (remove contact lenses if easily possible). 
Ingestion Blue lips, fingernails and skin. See Inhalation.  Do not eat, drink, or smoke during work.  Rinse mouth. Refer immediately for medical attention. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Do NOT let this chemical enter the environment. Sweep spilled substance into sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.  Do not transport with food and feedstuffs. 
EC Classification
 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: II 
GHS Classification
Signal: Danger
Harmful if swallowed
Toxic in contact with skin
Toxic to aquatic life
Causes damage to blood 
skull;toxiccancer;health haz

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61GT2-II and 61S1578.
NFPA Code: H2; F1; R; 0. 
Separated from combustible substances, reducing agents and food and feedstuffs. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing. 

IMPORTANT DATA
Physical State; Appearance
PALE YELLOW CRYSTALS WITH CHARACTERISTIC ODOUR. 

Physical dangers
Dust explosion possible if in powder or granular form, mixed with air. 

Chemical dangers
Decomposes on burning. This produces toxic and corrosive fumes including nitrogen oxides, chlorine (see ICSC 0126), hydrogen chloride (See ICSC 0163) and phosgene (see ICSC 0007). This generates fire and explosion hazard. The substance is a strong oxidant. It reacts with combustible and reducing materials. 

Occupational exposure limits
TLV (NOT-ESTABLISHED):.
MAK: Skin absorption (H); (DFG 2006). 

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion. 

Inhalation risk
A harmful concentration of airborne particles can be reached quickly when dispersed, especially if powdered. 

Effects of short-term exposure
The substance is mildly irritating to the eyes. The substance may cause effects on the blood. This may result in formation of methaemoglobin. The effects may be delayed. Medical observation is indicated. See Notes. 

Effects of long-term or repeated exposure
The substance may have effects on the blood. This may result in formation of methaemoglobin. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 236°C
Melting point: 44°C
Density: 1.3 g/cm³
Solubility in water at 20°C: very poor
Vapour pressure, Pa at 20°C: 5
Relative vapour density (air = 1): 5.44
Flash point: 103°C c.c.
Auto-ignition temperature: 500°C
Octanol/water partition coefficient as log Pow: 2.41  
The substance is toxic to aquatic organisms. It is strongly advised not to let the chemical enter into the environment. 

NOTES
TLV (as para-nitrochlorobenzene): 0.1 ppm (skin) A3 (confirmed animal carcinogen with unknown relevance to humans) BEI issued (ACGIH 2006).
See ICSC0028.
Depending on the degree of exposure, periodic medical examination is suggested.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
Rinse contaminated clothes with plenty of water because of fire hazard. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations