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METHYL VINYL KETONE
ICSC: 1495
Peer-Review Status: 27.11.2003 Validated
3-Buten-2-one
Methylene acetone 
CAS #: 78-94-4 RTECS #: EM9800000
UN #: 1251
EINECS #: 201-160-6
    Formula: C4H6O
Molecular mass: 70.1

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Highly flammable.  NO open flames, NO sparks and NO smoking.  Use water spray, powder, alcohol-resistant foam, carbon dioxide. 
EXPLOSION Vapour/air mixtures are explosive.  Closed system, ventilation, explosion-proof electrical equipment and lighting.  In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE   STRICT HYGIENE!   
Inhalation Burning sensation. Cough. Sore throat. Shortness of breath. Laboured breathing. Headache. Dizziness. Tremor. Symptoms may be delayed. See Notes.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention. 
Skin MAY BE ABSORBED! Redness. Pain. Skin burns. Further see Inhalation.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention . 
Eyes Watering of the eyes. Redness. Pain. Severe deep burns.  Wear face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Burning sensation. Abdominal pain. Shock or collapse. Further see Inhalation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Do NOT induce vomiting. Give one or two glasses of water to drink. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Remove all ignition sources. Personal protection: chemical protection suit including self-contained breathing apparatus. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.   
EC Classification
 
UN Classification
UN Hazard Class: 6.1; UN Subsidiary Risks: 3 and 8; UN Pack Group: I 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61S1251.
NFPA Code: H4; F3; R2. 
Fireproof. Cool. Keep in the dark. Separated from strong reducing agents, strong oxidants and strong bases. Store only if stabilized. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS-TO-YELLOW LIQUID WITH PUNGENT ODOUR. 

Physical dangers
The vapour is heavier than air and may travel along the ground; distant ignition possible. Vapours are uninhibited and may polymerize, causing blockage of vents. 

Chemical dangers
The substance polymerizes under the influence of peroxides, heat, light and oxidants. Reacts with strong bases, strong reducing agents and strong oxidants. 

Occupational exposure limits
TLV: 0.2ppm (ceiling value); (skin); (SEN); (ACGIH 2003).
MAK: Skin absorption (H); Sensitization of skin (SH); (DFG 2003). 

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion. 

Inhalation risk
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C. 

Effects of short-term exposure
Lachrymation. The substance is corrosive to the eyes and skin. Corrosive on ingestion. The vapour is severely irritating to the eyes and respiratory tract. Inhalation may cause lung oedema. See Notes. The substance may cause effects on the central nervous system. 

Effects of long-term or repeated exposure
Repeated or prolonged contact may cause skin sensitization. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 81°C
Melting point: -7°C
Relative density (water = 1): 0.86
Solubility in water: good
Vapour pressure, kPa at 25°C: 11
Relative vapour density (air = 1): 2.4
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.1
Flash point: -7°C c.c.
Auto-ignition temperature: 491°C
Explosive limits, vol% in air: 2.1-15.6
Octanol/water partition coefficient as log Pow: 0.117 (estimated) 
 

NOTES
The occupational exposure limit value should not be exceeded during any part of the working exposure.
The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort.
Rest and medical observation is therefore essential.
An added stabilizer or inhibitor can influence the toxicological properties of this substance, consult an expert.
Do NOT take working clothes home.
Card has been partly updated in April 2005.
See section Occupational Exposure Limits. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations