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ISOFLURANEICSC: 1435
Ether, 1-chloro-2,2,2-trifluoroethyl difluoromethyl
2-Chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane
May 2002
CAS #: 26675-46-7
EC Number: 247-897-7

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.        In case of fire in the surroundings, use appropriate extinguishing media.   

   
  SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat. Dizziness. Drowsiness. Headache. Unconsciousness. See Notes.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Artificial respiration may be needed. Refer for medical attention. 
Skin Redness. Dry skin.  Protective gloves.  Remove contaminated clothes. Rinse and then wash skin with water and soap. 
Eyes Redness. Pain.  Wear safety spectacles or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion See Inhalation.  Do not eat, drink, or smoke during work.  Rinse mouth. Refer for medical attention . 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Personal protection: self-contained breathing apparatus. Ventilation. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. 

According to UN GHS Criteria

 

Transportation
UN Classification
 

STORAGE
Ventilation along the floor. 
PACKAGING
 
ISOFLURANE ICSC: 1435
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS LIQUID. 

Physical dangers
The vapour is heavier than air and may accumulate in lowered spaces causing a deficiency of oxygen. 

Chemical dangers
Decomposes on contact with hot surfaces or flames. This produces toxic and corrosive fumes including phosgene, hydrogen chloride and hydrogen fluoride. 

Formula: C3H2ClF5O
Molecular mass: 184.5
Boiling point: 48.5°C
Relative density (water = 1): 1.5
Solubility in water: poor
Vapour pressure, kPa at 20°C: 32
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.2
Octanol/water partition coefficient as log Pow: 2.1  


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour and by ingestion. 

Effects of short-term exposure
The substance is irritating to the eyes and skin. The vapour is irritating to the respiratory tract. The substance may cause effects on the central nervous system and cardiovascular system. Exposure at high levels could cause unconsciousness. 

Inhalation risk
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C. 

Effects of long-term or repeated exposure
 


OCCUPATIONAL EXPOSURE LIMITS
 

ENVIRONMENT
 

NOTES
Check oxygen content before entering area.
High concentrations in the air cause a deficiency of oxygen with the risk of unconsciousness or death. 

ADDITIONAL INFORMATION
  EC Classification
 

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    See Also:
       Toxicological Abbreviations