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ISOFLURANE
ICSC: 1435
Peer-Review Status: 03.05.2002 Validated
Ether, 1-chloro-2,2,2-trifluoroethyl difluoromethyl
2-Chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane 
CAS #: 26675-46-7 RTECS #: KN6799000
EINECS #: 247-897-7
    Formula: C3H2ClF5O
Molecular mass: 184.5

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.    In case of fire in the surroundings, use appropriate extinguishing media. 
EXPLOSION      
 
EXPOSURE      
Inhalation Cough. Sore throat. Dizziness. Drowsiness. Headache. Unconciousness. See Notes.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Artificial respiration may be needed. Refer for medical attention. 
Skin Redness. Dry skin.  Protective gloves.  Remove contaminated clothes. Rinse and then wash skin with water and soap. 
Eyes Redness. Pain.  Wear safety spectacles or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion See Inhalation.  Do not eat, drink, or smoke during work.  Rinse mouth. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: self-contained breathing apparatus. Ventilation. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.   
EC Classification
 
UN Classification
 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
  Ventilation along the floor. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS LIQUID. 

Physical dangers
The vapour is heavier than air and may accumulate in lowered spaces causing a deficiency of oxygen. 

Chemical dangers
Decomposes on contact with hot surfaces or flames. This produces toxic and corrosive fumes including phosgene, hydrogen chloride and hydrogen fluoride. 

Occupational exposure limits
TLV (NOT-ESTABLISHED):. 

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour and by ingestion. 

Inhalation risk
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance is irritating to the eyes and skin. The vapour is irritating to the respiratory tract. The substance may cause effects on the central nervous system and cardiovascular system. Exposure at high levels could cause unconsciousness. 

Effects of long-term or repeated exposure
 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 48.5°C
Relative density (water = 1): 1.5
Solubility in water: poor
Vapour pressure, kPa at 20°C: 32
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.2
Octanol/water partition coefficient as log Pow: 2.1  
 

NOTES
Check oxygen content before entering area.
High concentrations in the air cause a deficiency of oxygen with the risk of unconsciousness or death.
Forane is a trade name.
Card has been partly updated in April 2005. See sections Physical properties, Occupational Exposure Limits. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations