IPCS INCHEM Home
PARACETAMOL
ICSC: 1330
Peer-Review Status: 11.11.2008 Validated
Acetaminophen
4'-Hydroxyacetanilide
p-Acetylaminophenol
N-(4-Hydroxyphenyl) acetamide 
CAS #: 103-90-2 RTECS #: AE4200000
EINECS #: 203-157-5
    Formula: C8H9NO2 / HOC6H4NHCOCH3
Molecular mass: 151.2

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible.  NO open flames.  Use powder, alcohol-resistant foam, water spray, carbon dioxide. 
EXPLOSION      
 
EXPOSURE   PREVENT DISPERSION OF DUST!   
Inhalation Cough.  Use local exhaust or breathing protection.  Fresh air, rest. 
Skin   Protective gloves.  Rinse and then wash skin with water and soap. 
Eyes Redness.  Wear safety goggles.  Rinse with plenty of water (remove contact lenses if easily possible). 
Ingestion   Do not eat, drink, or smoke during work.  Give one or two glasses of water to drink. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Do NOT let this chemical enter the environment.   
EC Classification
 
UN Classification
 
GHS Classification
Signal: Warning
May cause damage to liver and kidneys through prolonged or repeated exposure if swallowed
Toxic to aquatic life 
cancer;health haz

EMERGENCY RESPONSE SAFE STORAGE
  Provision to contain effluent from fire extinguishing. Store in an area without drain or sewer access. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS CRYSTALS OR CRYSTALLINE POWDER. 

Physical dangers
 

Chemical dangers
 

Occupational exposure limits
TLV not established.
MAK (not established):. 

Routes of exposure
The substance can be absorbed into the body by ingestion. 

Inhalation risk
A nuisance-causing concentration of airborne particles can be reached quickly. 

Effects of short-term exposure
 

Effects of long-term or repeated exposure
Ingestion may cause effects on the kidneys and liver. This may result in impaired functions. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: >500°C
Melting point: 169-170°C
Density: 1.3 g/cm³
Solubility in water, g/100ml at 20°C: 1.4 (moderate)
Relative vapour density (air = 1): 5.2
Auto-ignition temperature: 540°C
Explosive limits, vol% in air: 15 - ?
Octanol/water partition coefficient as log Pow: 0.49  
The substance is toxic to aquatic organisms. It is strongly advised not to let the chemical enter into the environment. 

NOTES
 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations
       Paracetamol (PIM 396)
       Paracetamol  (IARC Summary & Evaluation, Volume 73, 1999)