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HEXAMETHYLENETETRAMINEICSC: 1228
1,3,5,7-Tetraazaadamantane
Methenamine
Hexamine
1,3,5,7-Tetraazatricyclo(3.3.1.1(3,7))decane
August 2002
CAS #: 100-97-0
UN #: 1328
EC Number: 202-905-8

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Combustible. Gives off irritating or toxic fumes (or gases) in a fire.  Finely dispersed particles form explosive mixtures in air.  NO open flames.  Closed system, dust explosion-proof electrical equipment and lighting. Prevent deposition of dust.  Use water spray, foam, powder.   

 PREVENT DISPERSION OF DUST!  
  SYMPTOMS PREVENTION FIRST AID
Inhalation Cough.  Use local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin Redness. Pain.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes Redness. Pain.  Wear face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Abdominal pain. Nausea. Vomiting.  Do not eat, drink, or smoke during work.  Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer for medical attention . 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Personal protection: filter respirator for organic gases and particulates adapted to the airborne concentration of the substance. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Wash away remainder with plenty of water. 

According to UN GHS Criteria

 

Transportation
UN Classification
UN Hazard Class: 4.1; UN Pack Group: III 

STORAGE
Separated from strong acids and strong oxidants. Dry. 
PACKAGING
 
HEXAMETHYLENETETRAMINE ICSC: 1228
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
HYGROSCOPIC COLOURLESS CRYSTALS OR WHITE CRYSTALLINE POWDER. 

Physical dangers
Dust explosion possible if in powder or granular form, mixed with air. 

Chemical dangers
Decomposes on heating and on burning. This produces toxic and corrosive gases including formaldehyde, ammonia, hydrogen cyanide and nitrogen oxides. The solution in water is a weak base. Reacts with strong oxidants and strong acids. Attacks aluminium and zinc. 

Formula: C6H12N4
Molecular mass: 140.2
Sublimation point: ~260°C
Density: 1.33 g/cm³
Solubility in water: good
Relative vapour density (air = 1): 4.9
Flash point: 250°C c.c.
Auto-ignition temperature: 390°C
Octanol/water partition coefficient as log Pow: -2.84  


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol and by ingestion. 

Effects of short-term exposure
The substance is mildly irritating to the eyes and skin. 

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed. 

Effects of long-term or repeated exposure
Repeated or prolonged contact may cause skin sensitization. Repeated or prolonged inhalation may cause asthma. 


OCCUPATIONAL EXPOSURE LIMITS
MAK sensitization of skin (SH) 

ENVIRONMENT
 

NOTES
The substance may release formaldehyde.
See ICSC 0695.
Anyone who has shown symptoms of asthma due to this substance should avoid all further contact.
The symptoms of asthma often do not become manifest until a few hours have passed and they are aggravated by physical effort.
Rest and medical observation are therefore essential. 

ADDITIONAL INFORMATION
  EC Classification
Symbol: F, Xn; R: 11-42/43; S: (2)-16-22-24-37 

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    See Also:
       Toxicological Abbreviations
       Hexamethylenetetramine (FAO Nutrition Meetings Report Series 38a)
       Hexamethylenetetramine (WHO Food Additives Series 1)
       Hexamethylenetetramine (WHO Food Additives Series 5)
       HEXAMETHYLENETETRAMINE (JECFA Evaluation)