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PHORATE
ICSC: 1060
Peer-Review Status: 10.03.2000 Validated
O,O-Diethyl-S-(ethylthio)methyl phosphorodithioate 
CAS #: 298-02-2 RTECS #: TD9450000
UN #: 3018
EC #: 015-033-00-6
EINECS #: 206-052-2
    Formula: C7H17O2PS3
Molecular mass: 260.4

TYPES OF HAZARD
/ EXPOSURE
ACUTE HAZARDS / SYMPTOMS PREVENTION FIRST AID / FIRE-FIGHTING
FIRE Combustible.  NO open flames.  Use water spray, foam, powder, carbon dioxide. 
EXPLOSION      
 
EXPOSURE   STRICT HYGIENE!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Convulsions. Laboured breathing. Pupillary constriction, muscle cramp, excessive salivation. Sweating.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin MAY BE ABSORBED! See Inhalation.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes See Inhalation.  Wear safety goggles, face shield or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion See Inhalation. Abdominal cramps. Diarrhoea. Vomiting.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Give one or two glasses of water to drink. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment. Personal protection: gas-tight chemical protection suit including self-contained breathing apparatus.   
EC Classification
Symbol: T+, N; R: 27/28-50/53; S: (1/2)-28-36/37-45-60-61 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: I 
GHS Classification
Signal: Danger
Fatal if swallowed, in contact with skin or if inhaled
Causes damage to nervous system
Causes damage to the nervous system through prolonged or repeated exposure
Very toxic to aquatic life with long lasting effects 
skull;toxiccancer;health hazenviro;aqua

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61GT6-I.  Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Keep in a well-ventilated room. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS-TO-YELLOW LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
 

Chemical dangers
Decomposes under the influence of heat. This produces fumes of phosphorus oxides and sulfur oxides. 

Occupational exposure limits
TLV: 0.05mg/m³ as TWA; (skin); A4 (not classifiable as a human carcinogen); BEI issued; (ACGIH 2005). 

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin, through the eyes and by ingestion. 

Inhalation risk
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster. 

Effects of short-term exposure
The substance may cause effects on the central nervous system. This may result in cholinesterase inhibition. Exposure could cause death. Medical observation is indicated. The effects may be delayed. 

Effects of long-term or repeated exposure
Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Melting point: -42.9°C
Relative density (water = 1): 1.2
Solubility in water: none
Vapour pressure, Pa at 20°C: 0.1
Flash point: 160°C o.c.
Octanol/water partition coefficient as log Pow: 3.9  
The substance is very toxic to aquatic organisms. This substance may be hazardous to the environment. Special attention should be given to birds and bees. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal. 

NOTES
Do NOT take working clothes home.
Depending on the degree of exposure, periodic medical examination is suggested.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
Card has been partially updated in October 2005: see Occupational Exposure Limits; EU Classification; Emergency Response.
Card has been partially updated in November 2008: see Ingestion First Aid; Occupational Exposure Limits; Storage.
Card has been partially updated in April 2013: see GHS classification. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations
       Phorate (Pesticide residues in food: 1977 evaluations)
       Phorate (Pesticide residues in food: 1982 evaluations)
       Phorate (Pesticide residues in food: 1984 evaluations)
       Phorate (Pesticide residues in food: 1985 evaluations Part II Toxicology)
       Phorate (Pesticide residues in food: 1994 evaluations Part II Toxicology)
       Phorate (Pesticide residues in food: 1996 evaluations Part II Toxicological)