ICSC 1060 - PHORATE

PHORATE	ICSC: 1060 (March 2000)
O,O-Diethyl-S-(ethylthio)methyl phosphorodithioate

CAS #: 298-02-2

UN #: 3018

EC Number: 206-052-2

	ACUTE HAZARDS	PREVENTION	FIRE FIGHTING
FIRE & EXPLOSION	Combustible.	NO open flames.	Use water spray, foam, powder, carbon dioxide.

STRICT HYGIENE! IN ALL CASES CONSULT A DOCTOR!
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	Convulsions. Laboured breathing. Pupillary constriction, muscle cramp, excessive salivation. Sweating.	Use ventilation, local exhaust or breathing protection.	Fresh air, rest. Refer for medical attention.
Skin	MAY BE ABSORBED! See Inhalation.	Protective gloves. Protective clothing.	Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .
Eyes	See Inhalation.	Wear safety goggles, face shield or eye protection in combination with breathing protection.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion	See Inhalation. Abdominal cramps. Diarrhoea. Vomiting.	Do not eat, drink, or smoke during work. Wash hands before eating.	Rinse mouth. Give one or two glasses of water to drink. Refer for medical attention .

SPILLAGE DISPOSAL	CLASSIFICATION & LABELLING
Personal protection: gas-tight chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.	According to UN GHS Criteria DANGER Fatal if swallowed, in contact with skin or if inhaled Causes damage to nervous system Causes damage to the nervous system through prolonged or repeated exposure Very toxic to aquatic life with long lasting effects Transportation UN Classification UN Hazard Class: 6.1; UN Pack Group: I
STORAGE
Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Keep in a well-ventilated room. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing.
PACKAGING

PHORATE

ICSC: 1060

PHYSICAL & CHEMICAL INFORMATION
Physical State; Appearance COLOURLESS-TO-YELLOW LIQUID WITH CHARACTERISTIC ODOUR. Physical dangers Chemical dangers Decomposes under the influence of heat. This produces fumes of phosphorus oxides and sulfur oxides.	Formula: C₇H₁₇O₂PS₃ Molecular mass: 260.4 Melting point: -42.9°C Relative density (water = 1): 1.2 Solubility in water: none Vapour pressure, Pa at 20°C: 0.1 Flash point: 160°C o.c. Octanol/water partition coefficient as log Pow: 3.9

PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS-TO-YELLOW LIQUID WITH CHARACTERISTIC ODOUR.

Physical dangers

Chemical dangers
Decomposes under the influence of heat. This produces fumes of phosphorus oxides and sulfur oxides.

Formula: C₇H₁₇O₂PS₃
Molecular mass: 260.4
Melting point: -42.9°C
Relative density (water = 1): 1.2
Solubility in water: none
Vapour pressure, Pa at 20°C: 0.1
Flash point: 160°C o.c.
Octanol/water partition coefficient as log Pow: 3.9

EXPOSURE & HEALTH EFFECTS
Routes of exposure The substance can be absorbed into the body by inhalation, through the skin, through the eyes and by ingestion. Effects of short-term exposure The substance may cause effects on the central nervous system. This may result in cholinesterase inhibition. Exposure could cause death. Medical observation is indicated. The effects may be delayed.	Inhalation risk A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster. Effects of long-term or repeated exposure Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms.

EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin, through the eyes and by ingestion.

Effects of short-term exposure
The substance may cause effects on the central nervous system. This may result in cholinesterase inhibition. Exposure could cause death. Medical observation is indicated. The effects may be delayed.

Inhalation risk
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster.

Effects of long-term or repeated exposure
Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms.

OCCUPATIONAL EXPOSURE LIMITS
TLV: 0.05 mg/m³, as TWA; (skin); A4 (not classifiable as a human carcinogen); BEI issued

ENVIRONMENT
The substance is very toxic to aquatic organisms. This substance may be hazardous to the environment. Special attention should be given to birds and bees. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal.

NOTES
Do NOT take working clothes home. Depending on the degree of exposure, periodic medical examination is suggested. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.

ADDITIONAL INFORMATION

EC Classification
Symbol: T+, N; R: 27/28-50/53; S: (1/2)-28-36/37-45-60-61

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    See Also:
       Toxicological Abbreviations
       Phorate (Pesticide residues in food: 1977 evaluations)
       Phorate (Pesticide residues in food: 1982 evaluations)
       Phorate (Pesticide residues in food: 1984 evaluations)
       Phorate (Pesticide residues in food: 1985 evaluations Part II Toxicology)
       Phorate (Pesticide residues in food: 1994 evaluations Part II Toxicology)
       Phorate (Pesticide residues in food: 1996 evaluations Part II Toxicological)