BRUCINE, ANHYDROUS (ICSC)

BRUCINE, ANHYDROUS	ICSC: 1017

Date of peer-review: March 2002

10,11-Dimethoxystrychnine
2,3-Dimethoxystrychnidin-10-one
2,3-Dimethylstrychnine
Dimethoxystrychnine

CAS #

357-57-3

C₂₃H₂₆N₂O₄

RTECS #

EH8925000

Molecular mass: 394.47

UN #

1570

EC #

614-006-00-1

TYPES OF HAZARD / EXPOSURE	ACUTE HAZARDS / SYMPTOMS	PREVENTION	FIRST AID / FIRE FIGHTING
FIRE	Combustible. Gives off irritating or toxic fumes (or gases) in a fire.	NO open flames.	Powder, water spray, foam, carbon dioxide.
EXPLOSION

EXPOSURE		STRICT HYGIENE!	IN ALL CASES CONSULT A DOCTOR!
Inhalation	See Ingestion.	Ventilation (not if powder), local exhaust, or breathing protection.	Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.
Skin		Protective gloves.	Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.
Eyes	Redness.	Safety goggles.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
Ingestion	Headache. Nausea. Vomiting. Twiching. Excitement. Restlessness. Convulsions. Laboured breathing.	Do not eat, drink, or smoke during work. Wash hands before eating.	Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer for medical attention. Keep victim completely undisturbed.

SPILLAGE DISPOSAL

PACKAGING & LABELLING

Sweep spilled substance into sealable containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. (Extra personal protection: P3 filter respirator for toxic particles.) Do NOT let this chemical enter the environment.

Do not transport with food and feedstuffs.
EU Classification
Symbol: T+
R: 26/28-52/53
S: (1/2-)13-45-61
UN Classification
UN Hazard Class: 6.1
UN Pack Group: I

EMERGENCY RESPONSE

STORAGE

Transport Emergency Card: TEC (R)-61GT2-I

Separated from strong oxidants, food and feedstuffs. Dry. Well closed.

IPCS
International
Programme on
Chemical Safety

Prepared in the context of cooperation between the International Programme on Chemical Safety and the Commission of the European Communities © IPCS, CEC 1999

SEE IMPORTANT INFORMATION ON BACK

BRUCINE, ANHYDROUS

ICSC: 1017

IMPORTANT DATA

PHYSICAL STATE; APPEARANCE:
COLOURLESS CRYSTALS OR WHITE CRYSTALLINE POWDER

CHEMICAL DANGERS:
The substance decomposes on heating producing toxic fumes including nitrogen oxides. The solution in water is a weak base. Reacts with strong oxidants, causing fire and explosion hazard.

OCCUPATIONAL EXPOSURE LIMITS:
TLV not established.

ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.

INHALATION RISK:
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed, especially if powdered.

EFFECTS OF SHORT-TERM EXPOSURE:
May cause mechanical irritation. The substance may cause effects on the nervous system and eyes, resulting in convulsions and respiratory paralysis. Exposure may result in death.

PHYSICAL PROPERTIES

Boiling point: 470°C
Melting point: 178°C
Solubility in water: poor

Octanol/water partition coefficient as log Pow: 0.98

ENVIRONMENTAL DATA

The substance is harmful to aquatic organisms. This substance may be hazardous in the environment; special attention should be given to birds.

NOTES

Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. The recommendations on this Card also apply to Brucine hydrate (CAS 5892-11-5).

ADDITIONAL INFORMATION

LEGAL NOTICE

Neither the CEC nor the IPCS nor any person acting on behalf of the CEC or the IPCS is responsible for the use which might be made of this information

    See Also:
       Toxicological Abbreviations