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3-METHYL-2-BUTANONE
ICSC: 0922
Peer-Review Status: 25.03.1996 Validated
Methyl isopropyl ketone
2-Acetyl propane 
CAS #: 563-80-4 RTECS #: EL9100000
UN #: 2397
EC #: 606-007-00-0
EINECS #: 209-264-3
 		    Formula: C5H10O
Molecular mass: 86.13

TYPES OF
HAZARD /
EXPOSURE 		ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Highly flammable.  NO open flames, NO sparks and NO smoking.  Use foam, powder, carbon dioxide. 
EXPLOSION Vapour/air mixtures are explosive.  Closed system, ventilation, explosion-proof electrical equipment and lighting.  In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE   AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN!   
Inhalation Burning sensation. Cough. Laboured breathing.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin MAY BE ABSORBED! Redness.  Protective gloves.  Remove contaminated clothes. Rinse skin with plenty of water or shower. 
Eyes Redness. Pain.  Wear safety goggles or eye protection in combination with breathing protection.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Nausea. Vomiting. Weakness.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Refer for medical attention . 

SPILLAGE DISPOSAL
 		PACKAGING & LABELLING
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Absorb remaining liquid in dry sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT wash away into sewer.   
EC Classification
Symbol: F; R: 11; S: (2)-9-16-33 
UN Classification
UN Hazard Class: 3; UN Pack Group: II 
GHS Classification
 

EMERGENCY RESPONSE SAFE STORAGE
  Fireproof. Separated from flammable substances and strong oxidants. Well closed. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
The vapour is heavier than air and may travel along the ground; distant ignition possible. The vapour mixes well with air, explosive mixtures are easily formed. 

Chemical dangers
Decomposes on heating. This produces irritating fumes. Reacts vigorously with oxidants. 

Occupational exposure limits
TLV: 200ppm, 70mg/m³ as TWA; (ACGIH 1995). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion. 

Inhalation risk
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the central nervous system. This may result in narcosis and weakness. 

Effects of long-term or repeated exposure
The liquid defats the skin. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 93-95°C
Melting point: -92°C
Relative density (water = 1): 0.80
Solubility in water, g/100ml at 20°C: 0.6
Vapour pressure, kPa at 20°C: 5.5
Relative vapour density (air = 1): 2.9
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.10
Flash point: -1°C
Auto-ignition temperature: 475°C
Explosive limits, vol% in air: 1.2-8  		 

NOTES
 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety 		WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information. 
    See Also:
       Toxicological Abbreviations