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N-METHYLANILINE
ICSC: 0921
Peer-Review Status: 05.04.2006 Validated
N-Methylbenzenamine
Monomethylaniline
N-Methylphenylamine 
CAS #: 100-61-8 RTECS #: BY4550000
UN #: 2294
EC #: 612-015-00-5
EINECS #: 202-870-9
    Formula: C7H9N / C6H5NH(CH3)
Molecular mass: 107.2

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames.  Use water spray, powder, foam, carbon dioxide. 
EXPLOSION Above 79.5°C explosive vapour/air mixtures may be formed.  Above 79.5°C use a closed system and ventilation.   
 
EXPOSURE   PREVENT GENERATION OF MISTS! STRICT HYGIENE!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Blue lips, fingernails and skin. Cough. Dizziness. Headache. Laboured breathing. Sore throat.  Use local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin MAY BE ABSORBED! Further see Inhalation.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . 
Eyes   Wear face shield or eye protection in combination with breathing protection.  Rinse with plenty of water for several minutes (remove contact lenses if easily possible). 
Ingestion Abdominal pain. Blue lips, fingernails and skin. Dizziness. Headache. Laboured breathing. Nausea.  Do not eat, drink, or smoke during work.  Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer for medical attention . 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.  Do not transport with food and feedstuffs. 
EC Classification
Symbol: T, N; R: 23/24/25-33-50/53; S: (1/2)-28-36/37-45-60-61 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: III 
GHS Classification
Signal: Danger
Combustible liquid
Harmful if swallowed
Causes damage to blood
Harmful to aquatic life 
excl mark;warncancer;health haz

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61GT1-III.  Separated from strong oxidants, strong acids and food and feedstuffs. Keep in a well-ventilated room. Store in an area without drain or sewer access. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS OR SLIGHTLY YELLOW OILY LIQUID. TURNS BROWN ON EXPOSURE TO AIR. 

Physical dangers
 

Chemical dangers
Decomposes on heating and on burning. This produces toxic fumes including nitrogen oxides and aniline. Reacts violently with strong acids and oxidants. 

Occupational exposure limits
TLV: 0.5ppm as TWA; (skin); BEI issued; (ACGIH 2006).
MAK: 0.5 ppm, 2.2 mg/m³; Peak limitation category: II(2); Pregnancy risk group: D; Skin absorption (H); (DFG 2007). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour, by inhalation of its aerosol, through the skin and by ingestion. 

Inhalation risk
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance may cause effects on the blood. This may result in formation of methaemoglobin. The effects may be delayed. Medical observation is indicated. 

Effects of long-term or repeated exposure
 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 194-196°C
Melting point: -57°C
Relative density (water = 1): 0.99
Solubility in water: none
Vapour pressure, Pa at 20°C: 39.9
Relative vapour density (air = 1): 3.7
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.0
Flash point: 79.5°C c.c.
Octanol/water partition coefficient as log Pow: 1.7  
The substance is harmful to aquatic organisms. 

NOTES
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
Card has been partially updated in March 2008: see Occupational Exposure Limits, Storage. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations