IPCS INCHEM Home
ISOPROPANOLAMINEICSC: 0905 (June 2015)
1-Amino-2-propanol
Threamine
CAS #: 78-96-6
UN #: 2735
EC Number: 201-162-7

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Combustible. Gives off irritating or toxic fumes (or gases) in a fire.  Above 77°C explosive vapour/air mixtures may be formed.  NO open flames.  Above 77°C use a closed system and ventilation.  Use water spray, powder, alcohol-resistant foam, carbon dioxide.   

 AVOID ALL CONTACT! IN ALL CASES CONSULT A DOCTOR! 
  SYMPTOMS PREVENTION FIRST AID
Inhalation Sore throat. Cough. Burning sensation. Shortness of breath. Laboured breathing.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention. 
Skin Pain. Redness. Blisters. Skin burns.  Protective gloves. Protective clothing.  First rinse with plenty of water for at least 15 minutes, then remove contaminated clothes and rinse again. Refer for medical attention . 
Eyes Pain. Redness. Severe burns. Loss of vision.  Wear face shield or eye protection in combination with breathing protection.  Rinse with plenty of water for several minutes (remove contact lenses if easily possible). Refer immediately for medical attention. 
Ingestion Burning sensation. Burns in mouth and throat. Abdominal cramps. Shock or collapse.  Do not eat, drink, or smoke during work.  Rinse mouth. Give nothing to drink. Do NOT induce vomiting. Refer immediately for medical attention. 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. 

According to UN GHS Criteria

excl mark;warncorrcancer;health haz
DANGER
Combustible liquid
Harmful if swallowed or in contact with skin
Causes severe skin burns and eye damage
Causes damage to respiratory tract
May be harmful if swallowed and enters airways
Harmful to aquatic life 

Transportation
UN Classification
UN Hazard Class: 8; UN Pack Group: II 

STORAGE
Separated from strong oxidants and food and feedstuffs. See Chemical Dangers. Well closed. Keep in a well-ventilated room. Store in an area without drain or sewer access. 
PACKAGING
Do not transport with food and feedstuffs. 
ISOPROPANOLAMINE ICSC: 0905
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. 

Physical dangers
No data. 

Chemical dangers
On combustion, forms nitrogen oxides. Reacts violently with strong oxidants, cellulose nitrate, nitric acid and aldehydes. 

Formula: C3H9NO / CH3CHOHCH2NH2
Molecular mass: 75.11
Boiling point: 159.5°C
Melting point: 1°C
Density: 0.96 g/cm³
Solubility in water: soluble
Vapour pressure, kPa at 20°C: 0.2
Relative vapour density (air = 1): 2.6
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00
Flash point: 77°C c.c.
Auto-ignition temperature: 374°C
Explosive limits, vol% in air: 1.9-10.4
Octanol/water partition coefficient as log Pow: -1.0
Viscosity: 24 mm²/s at 25°C 


EXPOSURE & HEALTH EFFECTS

Routes of exposure
Serious local effects by all routes of exposure. 

Effects of short-term exposure
The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. Inhalation may cause lung oedema, but only after initial corrosive effects on eyes and/or airways have become manifest. Medical observation is indicated. If swallowed the substance may cause vomiting and could result in aspiration pneumonitis. 

Inhalation risk
No indication can be given whether a harmful concentration in the air will be reached. 

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. 


OCCUPATIONAL EXPOSURE LIMITS
 

ENVIRONMENT
The substance is harmful to aquatic organisms. 

NOTES
 

ADDITIONAL INFORMATION
  EC Classification
Symbol: C; R: 34; S: (1/2)-23-26-36-45 

All rights reserved. The published material is being distributed without warranty of any kind, either expressed or implied. Neither ILO nor WHO nor the European Commission shall be responsible for the interpretation and use of the information contained in this material.


    See Also:
       Toxicological Abbreviations