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2-HYDROXYPROPYL ACRYLATE
ICSC: 0899
Peer-Review Status: 31.03.2009 Validated
beta-Hydroxypropyl acrylate
1,2-propanediol-1-acrylate
Acrylic acid, 2-hydroxypropyl ester
Propylene glycol monoacrylate 
CAS #: 999-61-1 RTECS #: AT1925000
UN #: 2927
EC #: 607-108-00-2
EINECS #: 213-663-8
    Formula: C6H10O3 / CH2=CHCOOCH2CH(CH3)OH
Molecular mass: 130.2

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames.  Use water spray, dry powder, alcohol-resistant foam, carbon dioxide. 
EXPLOSION Above 65°C explosive vapour/air mixtures may be formed.  Above 65°C use a closed system and ventilation.  In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE   AVOID ALL CONTACT! PREVENT GENERATION OF MISTS!   
Inhalation Cough. Sore throat. Burning sensation. Shortness of breath. Laboured breathing.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Half-upright position. Refer immediately for medical attention. 
Skin MAY BE ABSORBED! Redness. Pain. Skin burns. Blisters.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower for at least 15 minutes. Refer immediately for medical attention. 
Eyes Redness. Pain. Blurred vision. Severe deep burns.  Wear face shield or eye protection in combination with breathing protection.  Rinse with plenty of water (remove contact lenses if easily possible). Refer immediately for medical attention. 
Ingestion Burns in mouth and throat. Abdominal pain. Vomiting. Shock or collapse.  Do not eat, drink, or smoke during work.  Rinse mouth. Do NOT induce vomiting. Refer immediately for medical attention. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking liquid in covered containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.  Do not transport with food and feedstuffs. 
EC Classification
Symbol: T; R: 23/24/25-34-43; S: (1/2)-26-36/37/39-45; Note: C, D 
UN Classification
UN Hazard Class: 6.1; UN Subsidiary Risks: 8; UN Pack Group: I 
GHS Classification
Signal: Danger
Combustible liquid
Toxic if swallowed
Fatal in contact with skin
Causes severe skin burns and eye damage
May cause an allergic skin reaction
May cause damage to respiratory tract if inhaled
May be harmful if swallowed and enters airways
Toxic to aquatic life 
corrskull;toxiccancer;health haz

EMERGENCY RESPONSE SAFE STORAGE
NFPA Code: H3; F1; R2.  Separated from food and feedstuffs. Cool. Keep in the dark. Store only if stabilized. See Notes. Provision to contain effluent from fire extinguishing. Store in an area without drain or sewer access. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS LIQUID. 

Physical dangers
No data. 

Chemical dangers
The substance may polymerize due to heating and under the influence of light, and peroxides. Decomposes on heating. This produces toxic and corrosive fumes including acrolein. Reacts violently with strong acids, strong bases, strong oxidants and peroxides. This generates fire hazard. 

Occupational exposure limits
 

Routes of exposure
The substance can be absorbed into the body through the skin and by ingestion. Serious local effects by all routes of exposure. 

Inhalation risk
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C. 

Effects of short-term exposure
The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. Inhalation may cause lung oedema, but only after initial corrosive effects on eyes and/or airways have become manifest. If swallowed the substance may cause vomiting and could result in aspiration pneumonitis. See Notes. 

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. Repeated or prolonged contact may cause skin sensitization. See Notes. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 191°C
Relative density (water = 1): 1.1
Solubility in water, g/100ml at 25°C: 100 (good)
Vapour pressure, Pa at 20°C: 5
Relative vapour density (air = 1): 4.5
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.0
Flash point: 65°C
Explosive limits, vol% in air: 1.4-?
Octanol/water partition coefficient as log Pow: 0.35  
The substance is toxic to aquatic organisms. It is strongly advised not to let the chemical enter into the environment. 

NOTES
Do NOT take working clothes home.
Skin cross-sensitization with other acrylates is possible.
An added stabilizer or inhibitor can influence the toxicological properties of this substance; consult an expert.
The effectiveness of phenolic inhibitors is dependent on the presence of oxygen. Store under air rather than inert atmosphere.
See ICSC 1742 Hydroxypropyl acrylate, isomers. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations