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alpha-HEXACHLOROCYCLOHEXANE
ICSC: 0795
Peer-Review Status: 25.11.2009 Validated
alpha-1,2,3,4,5,6-Hexachlorocyclohexane
alpha-Benzenehexachloride (alpha-BHC)
alpha-Hexachloran 
CAS #: 319-84-6 RTECS #: GV3500000
UN #: 2761
EC #: 602-042-00-0
EINECS #: 206-270-8
    Formula: C6H6Cl6
Molecular mass: 290.8

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Not combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.    In case of fire in the surroundings, use appropriate extinguishing media. 
EXPLOSION Risk of fire and explosion if formulations contain flammable/explosive solvents.    In case of fire: keep drums, etc., cool by spraying with water. 
 
EXPOSURE   AVOID ALL CONTACT! AVOID EXPOSURE OF BREASTFEEDING WOMEN!   
Inhalation Cough. Sore throat. See Ingestion.  Avoid inhalation of dust.  Fresh air, rest. Seek medical attention if you feel unwell. 
Skin MAY BE ABSORBED!  Protective gloves. Protective clothing.  Wear protective gloves when administering first aid. Remove contaminated clothes. Rinse and then wash skin with water and soap. Seek medical attention if you feel unwell. 
Eyes Redness.  Wear face shield or eye protection in combination with breathing protection.  Rinse with plenty of water (remove contact lenses if easily possible). 
Ingestion Headache. Nausea. Vomiting. Diarrhoea. Dizziness. Tremor. Convulsions.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Give a slurry of activated charcoal in water to drink, but NOT if convulsions occur. Refer immediately for medical attention. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: filter respirator for organic gases and particulates adapted to the airborne concentration of the substance, chemical protection suit including self-contained breathing apparatus and protective gloves. Do NOT let this chemical enter the environment. Sweep spilled substance into sealable non-metallic containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.  Do not transport with food and feedstuffs. 
EC Classification
Symbol: T, N; R: 21-25-40-50/53; S: (1/2)-22-36/37-45-60-61; Note: C 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: III 
GHS Classification
Signal: Danger
Toxic if swallowed
May be harmful in contact with skin
Suspected of causing cancer
May cause harm to breast-fed children
Causes damage to central nervous system
May cause damage to liver and kidneys through prolonged or repeated exposure
Very toxic to aquatic life with long lasting effects 
skull;toxiccancer;health hazenviro;aqua

EMERGENCY RESPONSE SAFE STORAGE
  Well closed. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing. Separated from bases, metals and food and feedstuffs. 

IMPORTANT DATA
Physical State; Appearance
BROWN-TO-WHITE CRYSTALLINE POWDER WITH CHARACTERISTIC ODOUR. 

Physical dangers
No data. 

Chemical dangers
Decomposes on contact with hot surfaces or flames. This produces toxic and corrosive fumes including chlorine (see ICSC 0126), hydrogen chloride (see ICSC 0163) and phosgene (see ICSC 0007). Reacts with bases and powdered metals. 

Occupational exposure limits
TLV not established.
MAK (inhalable fraction): 0.5 mg/m³; Peak limitation category: II(8); Skin absorption (H); (DFG 2009). 

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. 

Inhalation risk
A harmful concentration of airborne particles can be reached quickly when dispersed. 

Effects of short-term exposure
The substance may cause effects on the central nervous system. This may result in convulsions. 

Effects of long-term or repeated exposure
The substance may have effects on the central nervous system, kidneys and liver. This substance is probably carcinogenic to humans. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 288°C
Melting point: 157-160°C
Density: 1.9 g/cm³
Solubility in water: very poor
Vapour pressure, Pa at 20°C: 0.003
Relative vapour density (air = 1): 10
Octanol/water partition coefficient as log Pow: 3.8  
The substance is very toxic to aquatic organisms. Bioaccumulation of this chemical may occur along the food chain, for example in fish and seafood. The substance may cause long-term effects in the aquatic environment. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal. 

NOTES
This substance is a component of the insecticide hexachlorocyclohexane (mixed isomers).
Carrier solvents used in commercial formulations may change physical and toxicological properties.
The symptoms of convulsions do not become manifest until 0.5 to several hours.
Do NOT take working clothes home.
Do NOT use in the vicinity of a fire or a hot surface, or during welding.
Occupational Exposure Limits :MAK value is for technical mixture of alpha and beta isomers (0.5 mg/m3=(Conc.alpha-HCH divided by 5) + Conc beta-HCH])
See also ICSC #0053 (Lindane), #0487 (Hexachlorocyclohexane), #0796 (beta-Hexachlorocyclohexane). 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations