ICSC 0741 - DIMETHOATE

DIMETHOATE	ICSC: 0741 (March 1998)
O,O-Dimethyl S-methylcarbamoylmethyl phosphorodithioate Phosphorodithioic acid, O,O-dimethyl S-(2-(methylamino)-2-oxoethyl)ester O,O-Dimethyl S-(2-(methylamino)-2-oxoethyl)phosphorodithioate

CAS #: 60-51-5

UN #: 2783

EC Number: 200-480-3

	ACUTE HAZARDS	PREVENTION	FIRE FIGHTING
FIRE & EXPLOSION	Combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.	NO open flames.	Use water spray, powder, carbon dioxide.

PREVENT DISPERSION OF DUST! AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN!
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation	Pupillary constriction, muscle cramp, excessive salivation. Sweating. Nausea. Dizziness. Laboured breathing. Weakness.	Use ventilation (not if powder).	Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.
Skin	MAY BE ABSORBED! Further see Inhalation.	Protective gloves. Protective clothing.	Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention .
Eyes	Redness. Pain.	Wear safety goggles or face shield.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Ingestion	Abdominal cramps. Convulsions. Diarrhoea. Unconsciousness. Vomiting. Further see Inhalation.	Do not eat, drink, or smoke during work. Wash hands before eating.	Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Rest. Refer for medical attention .

SPILLAGE DISPOSAL	CLASSIFICATION & LABELLING
Do NOT wash away into sewer. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. Personal protection: chemical protection suit including self-contained breathing apparatus.	According to UN GHS Criteria Transportation UN Classification UN Hazard Class: 6.1; UN Pack Group: III
STORAGE
Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Keep in a well-ventilated room.
PACKAGING
Do not transport with food and feedstuffs. Severe marine pollutant.

DIMETHOATE

ICSC: 0741

PHYSICAL & CHEMICAL INFORMATION
Physical State; Appearance PURE: COLOURLESS CRYSTALS WITH CHARACTERISTIC ODOUR. Physical dangers Chemical dangers Decomposes on heating. This produces toxic fumes including nitrogen oxides, phosphorus oxides and sulfur oxides.	Formula: C₅H₁₂NO₃PS₂ / CH₃NHCOCH₂SPS(OCH₃)₂ Molecular mass: 229.2 Boiling point at 0.01kPa: 117°C Melting point: 51-52°C Density: 1.3 g/cm³ Solubility in water, g/100ml at 21°C: 2.5 Vapour pressure, Pa at 25°C: 0.001 Flash point: 107°C c.c. Octanol/water partition coefficient as log Pow: 0.5/0.8

PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
PURE: COLOURLESS CRYSTALS WITH CHARACTERISTIC ODOUR.

Physical dangers

Chemical dangers
Decomposes on heating. This produces toxic fumes including nitrogen oxides, phosphorus oxides and sulfur oxides.

Formula: C₅H₁₂NO₃PS₂ / CH₃NHCOCH₂SPS(OCH₃)₂
Molecular mass: 229.2
Boiling point at 0.01kPa: 117°C
Melting point: 51-52°C
Density: 1.3 g/cm³
Solubility in water, g/100ml at 21°C: 2.5
Vapour pressure, Pa at 25°C: 0.001
Flash point: 107°C c.c.
Octanol/water partition coefficient as log Pow: 0.5/0.8

EXPOSURE & HEALTH EFFECTS
Routes of exposure The substance can be absorbed into the body by inhalation, through the skin and by ingestion. Effects of short-term exposure The substance may cause effects on the nervous system at high levels. Cholinesterase inhibition. Exposure could cause death. The effects may be delayed. Medical observation is indicated.	Inhalation risk Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly. Effects of long-term or repeated exposure Repeated or prolonged contact with skin may cause dermatitis. Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms. Animal tests show that this substance possibly causes toxic effects upon human reproduction.

EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion.

Effects of short-term exposure
The substance may cause effects on the nervous system at high levels. Cholinesterase inhibition. Exposure could cause death. The effects may be delayed. Medical observation is indicated.

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly.

Effects of long-term or repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms. Animal tests show that this substance possibly causes toxic effects upon human reproduction.

OCCUPATIONAL EXPOSURE LIMITS

ENVIRONMENT
The substance is toxic to aquatic organisms. This substance may be hazardous to the environment. Special attention should be given to bees and birds. Avoid release to the environment in circumstances different to normal use.

NOTES
Other melting points: 43-45°C (technical product). Depending on the degree of exposure, periodic medical examination is suggested. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. If the substance is formulated with solvent(s) also consult the card(s) (ICSC) of the solvent(s). Carrier solvents used in commercial formulations may change physical and toxicological properties.

NOTES

Other melting points: 43-45°C (technical product).
Depending on the degree of exposure, periodic medical examination is suggested.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.
If the substance is formulated with solvent(s) also consult the card(s) (ICSC) of the solvent(s).
Carrier solvents used in commercial formulations may change physical and toxicological properties.

ADDITIONAL INFORMATION

EC Classification
Symbol: Xn; R: 21/22; S: (2)-36/37

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    See Also:
       Toxicological Abbreviations
       Dimethoate (EHC 90, 1989)
       Dimethoate (HSG 20, 1988)
       Dimethoate (FAO Meeting Report PL/1965/10/1)
       Dimethoate (FAO/PL:CP/15)
       Dimethoate (FAO/PL:1967/M/11/1)
       Dimethoate (JMPR Evaluations 2003 Part II Toxicological)
       Dimethoate (AGP:1970/M/12/1)
       Dimethoate (Pesticide residues in food: 1983 evaluations)
       Dimethoate (Pesticide residues in food: 1984 evaluations)
       Dimethoate (Pesticide residues in food: 1984 evaluations)
       Dimethoate (Pesticide residues in food: 1987 evaluations Part II Toxicology)
       Dimethoate (Pesticide residues in food: 1996 evaluations Part II Toxicological)