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TRIMETHYL PHOSPHATEICSC: 0686
Phosphoric acid trimethyl ester
Trimethyl orthophosphate
October 2004
CAS #: 512-56-1
EC Number: 208-144-8

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Combustible. Gives off irritating or toxic fumes (or gases) in a fire.    NO open flames.    Use water spray, alcohol-resistant foam, dry powder, carbon dioxide.   

 AVOID ALL CONTACT!  
  SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Sore throat.  Use ventilation, local exhaust or breathing protection.  Fresh air, rest. Refer for medical attention. 
Skin Redness.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. 
Eyes Redness.  Wear safety goggles.  First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention. 
Ingestion Shortness of breath. Weakness. Hyperexcitability. Tremor.  Do not eat, drink, or smoke during work.  Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention . 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Personal protection: chemical protection suit including self-contained breathing apparatus. Ventilation. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. 

According to UN GHS Criteria

 

Transportation
UN Classification
 

STORAGE
Separated from strong oxidants and strong bases. 
PACKAGING
 
TRIMETHYL PHOSPHATE ICSC: 0686
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS LIQUID. 

Physical dangers
 

Chemical dangers
Decomposes on burning. This produces toxic fumes including phosphorus oxides. Reacts with strong bases and strong oxidants. May explode on heating during large scale atmospheric pressure distillation. 

Formula: C3H9O4P / (CH3O)3PO
Molecular mass: 140.1
Boiling point: 197.2°C
Melting point: -46°C
Relative density (water = 1): 1.2
Solubility in water, g/100ml at 25°C: 50 (good)
Vapour pressure, kPa at 20°C: 0.11
Flash point: 107°C
Octanol/water partition coefficient as log Pow: -0.52,-0.78  


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion. 

Effects of short-term exposure
The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the nervous system. 

Inhalation risk
No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20°C. 

Effects of long-term or repeated exposure
The substance may have effects on the nervous system. This may result in flaccid paralysis. May cause heritable genetic damage to human germ cells. 


OCCUPATIONAL EXPOSURE LIMITS
MAK: sensitization of skin (SH); carcinogen category: 3B; germ cell mutagen group: 2 

ENVIRONMENT
 

NOTES
 

ADDITIONAL INFORMATION
  EC Classification
 

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    See Also:
       Toxicological Abbreviations
       Trimethyl phosphate (SIDS)