IPCS INCHEM Home
2-AMINO-5-CHLOROTOLUENEICSC: 0630
4-Chloro-o-toluidine
4-Chloro-2-methylaniline
April 2007
CAS #: 95-69-2
UN #: 2239
EC Number: 202-441-6

  ACUTE HAZARDS PREVENTION FIRE FIGHTING
FIRE & EXPLOSION Combustible. Gives off irritating or toxic fumes (or gases) in a fire.    NO open flames.    Use water spray, dry powder, carbon dioxide.   

 AVOID ALL CONTACT! IN ALL CASES CONSULT A DOCTOR! 
  SYMPTOMS PREVENTION FIRST AID
Inhalation Cough. Red urine. Frequent, sudden and painful urination. Abdominal pain. Blue lips, fingernails and skin. Headache. Dizziness. Nausea. Drowsiness.  Use breathing protection.  Fresh air, rest. Refer immediately for medical attention. 
Skin Redness. MAY BE ABSORBED! See Inhalation.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer immediately for medical attention. 
Eyes Redness. Pain.  Wear face shield or eye protection in combination with breathing protection if powder.  Rinse with plenty of water for several minutes (remove contact lenses if easily possible). Refer for medical attention. 
Ingestion See Inhalation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Give one or two glasses of water to drink. Refer immediately for medical attention. 

SPILLAGE DISPOSAL CLASSIFICATION & LABELLING
Sweep spilled substance into covered containers. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment. 

According to UN GHS Criteria

excl mark;warncancer;health haz
DANGER
Harmful if swallowed
Harmful in contact with skin
May cause genetic defects
May cause cancer
Causes damage to bladder and red blood cells
Harmful to aquatic life
Harmful to aquatic life with long lasting effects 

Transportation
UN Classification
UN Hazard Class: 6.1; UN Pack Group: III 

STORAGE
Cool. Separated from food and feedstuffs. See Chemical Dangers. Well closed. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing. 
PACKAGING
Note: E 
2-AMINO-5-CHLOROTOLUENE ICSC: 0630
PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS TO BROWN SOLID IN VARIOUS FORMS OR LIQUID 

Physical dangers
 

Chemical dangers
Decomposes on burning. This produces toxic and corrosive fumes including hydrogen chloride and nitrogen oxides. Reacts violently with chloroformic acid esters, strong oxidants, acid anhydrides, acids and acid chlorides. 

Formula: C7H8ClN/ ClC6H3(CH3)NH2
Molecular mass: 141.6
Boiling point: 241°C
Melting point: 29-30°C
Density: 1.19 g/cm³
Solubility in water, g/100ml at 25°C: 0.095 (very poor)
Vapour pressure, Pa at 25°C: 5.5
Relative vapour density (air = 1): 4.9
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00
Flash point: 99°C c.c.
Auto-ignition temperature: 560°C
Octanol/water partition coefficient as log Pow: 2.27  


EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body through the skin, by inhalation and by ingestion. 

Effects of short-term exposure
May cause mechanical irritation to the skin, respiratory tract and eyes (as a solid). The substance may cause effects on the bladder. This may result in haemorrhagic inflammation. The substance may cause effects on the blood. This may result in the formation of methaemoglobin. The effects may be delayed. Medical observation is indicated. See Notes. 

Inhalation risk
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster. 

Effects of long-term or repeated exposure
May cause heritable genetic damage to human germ cells. 


OCCUPATIONAL EXPOSURE LIMITS
MAK: skin absorption (H); carcinogen category: 1; germ cell mutagen group: 3A 

ENVIRONMENT
The substance is harmful to aquatic organisms. It is strongly advised not to let the chemical enter into the environment. 

NOTES
Depending on the degree of exposure, periodic medical examination is suggested.
Do NOT take working clothes home.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. 

ADDITIONAL INFORMATION
  EC Classification
Symbol: T, N; R: 45-23/24/25-68-50/53; S: 53-45-61-60 

All rights reserved. The published material is being distributed without warranty of any kind, either expressed or implied. Neither ILO nor WHO nor the European Commission shall be responsible for the interpretation and use of the information contained in this material.
    See Also:
       Toxicological Abbreviations