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2-AMINO-5-CHLOROTOLUENE
ICSC: 0630
Peer-Review Status: 19.04.2007 Validated
4-Chloro-o-toluidine
4-Chloro-2-methylaniline 
CAS #: 95-69-2 RTECS #: XU5000000
UN #: 2239
EC #: 612-196-00-0
EINECS #: 202-441-6
    Formula: C7H8ClN/ ClC6H3(CH3)NH2
Molecular mass: 141.6

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire.  NO open flames.  Use water spray, dry powder, carbon dioxide. 
EXPLOSION      
 
EXPOSURE   AVOID ALL CONTACT!  IN ALL CASES CONSULT A DOCTOR! 
Inhalation Cough. Red urine. Frequent, sudden and painful urination. Abdominal pain. Blue lips, fingernails and skin. Headache. Dizziness. Nausea. Drowsiness.  Use breathing protection.  Fresh air, rest. Refer immediately for medical attention. 
Skin Redness. MAY BE ABSORBED! See Inhalation.  Protective gloves. Protective clothing.  Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer immediately for medical attention. 
Eyes Redness. Pain.  Wear face shield or eye protection in combination with breathing protection if powder.  Rinse with plenty of water for several minutes (remove contact lenses if easily possible). Refer for medical attention. 
Ingestion See Inhalation.  Do not eat, drink, or smoke during work. Wash hands before eating.  Rinse mouth. Give one or two glasses of water to drink. Refer immediately for medical attention. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Sweep spilled substance into covered containers. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment.  Note: E 
EC Classification
Symbol: T, N; R: 45-23/24/25-68-50/53; S: 53-45-61-60 
UN Classification
UN Hazard Class: 6.1; UN Pack Group: III 
GHS Classification
Signal: Danger
Harmful if swallowed
Harmful in contact with skin
May cause genetic defects
May cause cancer
Causes damage to bladder and red blood cells
Harmful to aquatic life
Harmful to aquatic life with long lasting effects 
excl mark;warncancer;health haz

EMERGENCY RESPONSE SAFE STORAGE
Transport Emergency Card: TEC (R)-61GT2-III.  Cool. Separated from food and feedstuffs. See Chemical Dangers. Well closed. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing. 

IMPORTANT DATA
Physical State; Appearance
COLOURLESS TO BROWN SOLID IN VARIOUS FORMS OR LIQUID 

Physical dangers
 

Chemical dangers
Decomposes on burning. This produces toxic and corrosive fumes including hydrogen chloride and nitrogen oxides. Reacts violently with chloroformic acid esters, strong oxidants, acid anhydrides, acids and acid chlorides. 

Occupational exposure limits
TLV (NOT-ESTABLISHED):.
MAK: Carcinogen category: 1; Germ cell mutagen group: 3A; Skin absorption (H); (DFG 2006). 

Routes of exposure
The substance can be absorbed into the body through the skin, by inhalation and by ingestion. 

Inhalation risk
A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster. 

Effects of short-term exposure
May cause mechanical irritation to the to the skin, respiratory tract and eyes (as a solid). The substance may cause effects on the bladder. This may result in haemorrhagic inflammation. The substance may cause effects on the blood. This may result in formation of methaemoglobin. The effects may be delayed. Medical observation is indicated. See Notes. 

Effects of long-term or repeated exposure
May cause heritable genetic damage to human germ cells. 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 241°C
Melting point: 29-30°C
Density: 1.19 g/cm³
Solubility in water, g/100ml at 25°C: 0.095 (very poor)
Vapour pressure, Pa at 25°C: 5.5
Relative vapour density (air = 1): 4.9
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00
Flash point: 99°C c.c.
Auto-ignition temperature: 560°C
Octanol/water partition coefficient as log Pow: 2.27  
The substance is harmful to aquatic organisms. It is strongly advised not to let the chemical enter into the environment. 

NOTES
Depending on the degree of exposure, periodic medical examination is suggested.
Do NOT take working clothes home.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations