IPCS INCHEM Home
DIETHYLENE GLYCOL
ICSC: 0619
Peer-Review Status: 23.11.2007 Validated
Ethylene diglycol
2,2'-Dihydroxyethyl ether
3-Oxypentane-1,5-diol
2,2'-Oxydiethanol
2,2'-Oxybisethanol 
CAS #: 111-46-6 RTECS #: ID5950000
EC #: 603-140-00-6
EINECS #: 203-872-2
    Formula: C4H10O3 / (CH2CH2OH)2O
Molecular mass: 106.1

TYPES OF
HAZARD /
EXPOSURE
ACUTE HAZARDS / SYMPTOMS      PREVENTION      FIRST AID / FIRE FIGHTING
FIRE Combustible.  NO open flames.  Use powder, alcohol-resistant foam, water spray, carbon dioxide. 
EXPLOSION      
 
EXPOSURE   PREVENT GENERATION OF MISTS!   
Inhalation   Use ventilation.  Fresh air, rest. 
Skin   Protective gloves.  Rinse skin with plenty of water or shower. 
Eyes   Wear safety spectacles.  Rinse with plenty of water for several minutes (remove contact lenses if easily possible). 
Ingestion Abdominal pain. Nausea. Vomiting. Diarrhoea. Dizziness. Drowsiness. Confusion. Unconsciousness.  Do not eat, drink, or smoke during work.  Give one or two glasses of water to drink. Rinse mouth. Refer immediately for medical attention. See Notes. 

SPILLAGE DISPOSAL
PACKAGING & LABELLING
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Collect leaking and spilled liquid in sealable containers as far as possible. Wash away remainder with plenty of water.   
EC Classification
Symbol: Xn; R: 22; S: (2)-46 
UN Classification
 
GHS Classification
Signal: Danger
Harmful if swallowed
Causes damage to kidneys if if swallowed
May cause drowsiness and dizziness 
excl mark;warncancer;health haz

EMERGENCY RESPONSE SAFE STORAGE
NFPA Code: H1; F1; R0.  Dry. Well closed. Separated from strong oxidants. 

IMPORTANT DATA
Physical State; Appearance
ODOURLESS COLOURLESS VISCOUS HYGROSCOPIC LIQUID. 

Physical dangers
 

Chemical dangers
Reacts violently with strong oxidants. This generates fire and explosion hazard. Attacks some forms of plastic. 

Occupational exposure limits
TLV (NOT-ESTABLISHED):.
MAK: 10 ppm, 44 mg/m³; Peak limitation category: II(4); Pregnancy risk group: C; (DFG 2007). 

Routes of exposure
The substance can be absorbed into the body by ingestion. 

Inhalation risk
A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster. 

Effects of short-term exposure
The substance may cause effects on the kidneys. This may result in kidney impairment. Ingestion could cause effects on the central nervous system and liver. Ingestion could cause death. 

Effects of long-term or repeated exposure
 


PHYSICAL PROPERTIES ENVIRONMENTAL DATA
Boiling point: 245°C
Melting point: -6.5°C
Relative density (water = 1): 1.12
Solubility in water: miscible
Vapour pressure, Pa at 20°C: 2.7
Relative vapour density (air = 1): 3.7
Flash point: 124°C c.c.
Auto-ignition temperature: 229°C
Explosive limits, vol% in air: 1.6-10.8
Octanol/water partition coefficient as log Pow: -1.47  
 

NOTES
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. 

ADDITIONAL INFORMATION
 

IPCS
International
Programme on
Chemical Safety
WHO ILO EC Prepared in the context of cooperation between the International Programme on Chemical Safety and the European Commission
© IPCS 2004-2012
LEGAL NOTICE Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible for the use which might be made of this information.


    See Also:
       Toxicological Abbreviations
       DIETHYLENE GLYCOL (JECFA Evaluation)